• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Therapeutic delivery >Recent advances in amphiphilic polymers for simultaneous delivery of hydrophobic and hydrophilic drugs.
【24h】

Recent advances in amphiphilic polymers for simultaneous delivery of hydrophobic and hydrophilic drugs.

机译：两亲性聚合物可同时递送疏水性和亲水性药物的最新进展。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Nanomedicine has evolved with the use of biological compounds such as proteins, peptides and DNA. These hydrophilic and often highly charged compounds require a delivery system to allow effective transport and release at the site of action. These new biological therapeutics have not replaced the more traditional smaller molecule, but instead are working synergistically to the benefit of the end user. To that end, drug delivery systems are now required to encapsulate both larger hydrophilic compounds as well as the smaller and generally more hydrophobic compound. This review highlights the emerging role in drug delivery of amphiphilic polymers that by their very nature can associate with compounds of differing physicochemical properties, in particular the role of micelles, polymersomes and nanocapsules.
机译：纳米医学已经随着诸如蛋白质，肽和DNA的生物化合物的使用而发展。这些亲水性且常常带高电荷的化合物需要一种递送系统以允许在作用部位有效地运输和释放。这些新的生物疗法并未取代更传统的较小分子，而是协同工作，为最终用户带来利益。为此，现在需要药物递送系统包封较大的亲水性化合物以及较小且通常更疏水的化合物。这篇综述强调了两亲性聚合物在药物传递中的新兴作用，由于其本身的性质，它们可以与具有不同理化性质的化合物结合，特别是胶束，聚合物小体和纳米胶囊的作用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号