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Hepatitis E: a neglected threat.

机译:戊型肝炎:被忽视的威胁。

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摘要

Hepatitis E, responsible for explosive waterborne outbreaks and sporadic cases of acute hepatitis in developing countries, affects predominantly young adults and has a fatality rate as high as 25% in pregnant women. No effective treatment exists for hepatitis E; however, a vaccine using a baculovirus-expressed recombinant hepatitis E capsid protein was recently studied in Nepal. In this review, the progress made in hepatitis E research and the recently concluded vaccine trial of the recombinant protein vaccine are briefly discussed.
机译:戊型肝炎是造成发展中国家爆发性水源性疾病暴发和急性肝炎偶发病例的主要原因,主要影响年轻人,孕妇的致死率高达25%。没有有效的治疗戊型肝炎的方法。但是,最近在尼泊尔研究了使用杆状病毒表达的重组戊型肝炎衣壳蛋白的疫苗。在这篇综述中,简要讨论了戊型肝炎研究的进展以及重组蛋白疫苗最近结束的疫苗试验。

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