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首页> 外文期刊>Transactions of the Royal Society of Tropical Medicine and Hygiene >Comparison of the Kato-Katz thick smear and McMaster egg counting techniques for monitoring drug efficacy against soil-transmitted helminths in schoolchildren on Pemba Island, Tanzania
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Comparison of the Kato-Katz thick smear and McMaster egg counting techniques for monitoring drug efficacy against soil-transmitted helminths in schoolchildren on Pemba Island, Tanzania

机译:坦桑尼亚彭巴岛小学生用加藤-卡茨厚涂片和McMaster卵计数技术监测对土壤传播的蠕虫的药效的比较

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摘要

The Kato-Katz thick smear technique is widely used to assess prevalence and intensity in soil-transmitted helminth (STH) control programmes, but its usefulness in monitoring anthelminthic drug efficacy needs to be validated and compared with other methods. A promising alternative is the McMaster egg counting technique. In the present study, the efficacy of single-dose albendazole against STH infections in 430 schoolchildren on Pemba Island was assessed using both the Kato-Katz and McMaster techniques. The study revealed comparable drug efficacy results for both methods and confirmed the potency of the McMaster technique as an alternative method for monitoring large-scale deworming programmes.
机译:Kato-Katz浓密涂片技术已广泛用于评估土壤传播蠕虫(STH)控制程序中的患病率和强度,但需要验证其在监测驱虫药功效方面的有用性,并与其他方法进行比较。一种有前途的替代方法是McMaster鸡蛋计数技术。在本研究中,使用Kato-Katz和McMaster技术评估了单剂量的阿苯达唑对奔巴岛上430名学童的STH感染的疗效。这项研究揭示了两种方法可比的药物功效结果,并证实了McMaster技术作为监测大规模驱虫程序的替代方法的效力。

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