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首页> 外文期刊>Transactions of the Royal Society of Tropical Medicine and Hygiene >Prevalence of antibodies against three species of Leishmania (L. mexicana, L. braziliensis, L. infantum) and possible associated factors in dogs from Mérida, Yucatán, Mexico
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Prevalence of antibodies against three species of Leishmania (L. mexicana, L. braziliensis, L. infantum) and possible associated factors in dogs from Mérida, Yucatán, Mexico

机译：在墨西哥尤卡坦州梅里达市的犬中，针对三种利什曼原虫（墨西哥乳杆菌，巴西乳杆菌，婴儿乳杆菌）的抗体及其相关因子的患病率

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摘要

Leishmania spp. has been recorded in humans and in dogs, and numerous studies have demonstrated that dogs act as reservoirs for visceral leishmaniasis. The objective of this study was to determine the prevalence of three species of the Leishmania genus and possible associated factors in sera of 218 dogs from two different populations in Mérida, Yucatán (Mexico). The sera were analyzed to detect antibodies against L. mexicana, L. braziliensis, and L. infantum using the superoxide dismutase- enzyme-linked immunosorbent assay (SOD-ELISA) and Western blot as confirmation. The Fe-SOD excreted was used as the antigenic fraction for the three Leishmania species. The prevalence values found were 30.2% (. L. mexicana), 8.2% (. L. braziliensis), and 11.9% (. L. infantum). , with L. mexicana seroprevalence being greater than L. braziliensis and L. infantum (p. <. 0.05). Five percent (11/218) of the dogs showed antibodies against L. mexicana/L. braziliensis, 5.5% (12/218) with L. mexicana/L. infantum and 1.8% (4/218) with L. mexicana/L. braziliensis/L. infantum. No relationship (p. >. 0.05. ) was found between antibodies against L. mexicana and breed, age, physical condition, or cutaneous lesions in dogs. This study provides evidence of antibodies against L. mexicana, L. braziliensis and L. infantum in dog populations from Mérida, Mexico.
机译：利什曼原虫属已经在人和狗中记录了这种病毒，许多研究表明，狗充当内脏利什曼病的储存库。这项研究的目的是确定来自尤卡坦州梅里达市（墨西哥）两个不同种群的218只狗的血清中三种利什曼原虫属的患病率和可能的相关因素。使用超氧化物歧化酶-酶联免疫吸附测定（SOD-ELISA）和Western印迹作为确认，分析血清以检测针对墨西哥乳杆菌，巴西乳杆菌和婴儿乳杆菌的抗体。分泌的Fe-SOD用作三种利什曼原虫物种的抗原级分。发现的患病率分别为30.2％（墨西哥乳杆菌），8.2％（巴西乳杆菌）和11.9％（婴儿乳杆菌）。 ，其中墨西哥乳杆菌的血清阳性率高于巴西乳杆菌和婴儿乳杆菌（p。<。0.05）。百分之五（11/218）的狗显示出针对墨西哥乳杆菌/ L的抗体。墨西哥乳杆菌/ L 5.5％（12/218）。墨西哥乳杆菌/ L。婴儿和1.8％（4/218）。巴西利亚/ L。婴儿。没有发现针对墨西哥乳杆菌的抗体与狗的品种，年龄，身体状况或皮肤损伤之间有相关性（p。> 0.05。）。这项研究提供了来自墨西哥梅里达的狗群中针对墨西哥乳杆菌，巴西乳杆菌和婴儿乳杆菌的抗体的证据。

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