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首页> 外文期刊>Transactions of the American Ophthalmological Society. >Vision and quality-of-life.
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Vision and quality-of-life.

机译：愿景和生活质量。

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OBJECTIVE: To determine the relationship of visual acuity loss to quality of life. DESIGN: Three hundred twenty-five patients with visual loss to a minimum of 20/40 or greater in at least 1 eye were interviewed in a standardized fashion using a modified VF-14, questionnaire. Utility values were also obtained using both the time trade-off and standard gamble methods of utility assessment. MAIN OUTCOME MEASURES: Best-corrected visual acuity was correlated with the visual function score on the modified VF-14 questionnaire, as well as with utility values obtained using both the time trade-off and standard gamble methods. RESULTS: Decreasing levels of vision in the eye with better acuity correlated directly with decreasing visual function scores on the modified VF-14 questionnaire, as did decreasing utility values using the time trade-off method of utility evaluation. The standard gamble method of utility evaluation was not as directly correlated with vision as the time trade-off method. Age, level of education, gender, race, length of time of visual loss, and the number of associated systemic comorbidities did not significantly affect the time trade-off utility values associated with visual loss in the better eye. The level of reduced vision in the better eye, rather than the specific disease process causing reduced vision, was related to mean utility values. The average person with 20/40 vision in the better seeing eye was willing to trade 2 of every 10 years of life in return for perfect vision (utility value of 0.8), while the average person with counting fingers vision in the better eye was willing to trade approximately 5 of every 10 remaining years of life (utility value of 0.52) in return for perfect vision. CONCLUSIONS: The time trade-off method of utility evaluation appears to be an effective method for assessing quality of life associated with visual loss. Time trade-off utility values decrease in direct conjunction with decreasing vision in the better-seeing eye. Unlike the modified VF-14 test and its counterparts, utility values allow the quality of life associated with visual loss to be more readily compared to the quality of life associated with other health (disease) states. This information can be employed for cost-effective analyses that objectively compare evidence-based medicine, patient-based preferences and sound econometric principles across all specialties in health care.
机译：目的：确定视力下降与生活质量的关系。设计：使用改良的VF-14问卷以标准化方式采访了325名视力丧失至少在1只眼中至少达到20/40或更大的患者。使用时间权衡和效用评估的标准赌博方法也可以获得效用值。主要观察指标：最佳矫正视力与修改后的VF-14问卷上的视觉功能评分以及使用时间权衡和标准赌博方法获得的效用值相关。结果：视力下降，视敏度提高与修改后的VF-14问卷上的视觉功能评分下降直接相关，使用效用评估的时间权衡方法降低效用值也是如此。效用评估的标准赌博方法不像时间权衡方法那样直接与愿景相关。年龄，受教育程度，性别，种族，视力丧失的时间长短以及相关的系统合并症的数量并没有显着影响与更好的视力有关的时间权衡效用值。更好的眼睛中视力下降的水平，而不是导致视力下降的特定疾病过程，与平均效用值有关。视力较好的人的平均视力为20/40，愿意换取每10年寿命中的2个以换取完美视力（效用值为0.8），而视力较好的人的平均手指数为视力，则愿意每剩余10年寿命中大约有5年（实用价值0.52）进行交易，以换取完美的视野。结论：效用评估的时间权衡方法似乎是评估与视力丧失相关的生活质量的有效方法。时间权衡的效用值直接与视力下降的视力下降直接相关。与修改后的VF-14测试及其对应的测试不同，实用价值使与视力丧失相关的生活质量相比于与其他健康（疾病）状态相关的生活质量更加容易。此信息可用于进行成本效益分析，从而客观地比较医疗保健所有专业中的循证医学，基于患者的偏好和合理的计量经济学原则。

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