• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Transactions of the American Ophthalmological Society. >CONGENITAL ABERRANT TEARING: A RE-LOOK
【24h】

CONGENITAL ABERRANT TEARING: A RE-LOOK

机译：先天性撕裂：重看

获取原文
获取原文并翻译 | 示例
       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Purpose: Congenital aberrant tearing is characterized by tearing when eating ("crocodile tears"), lack of emotional tearing, or both. Most reported cases are associated with Duane syndrome. In our previous studies we observed aberrant tearing in individuals with thalidomide embryopathy and M?bius sequence. This report summarizes the literature on the subject and adds 3 new studies that give information on this unusual condition. Methods: Twenty-eight individuals with M?bius sequence were interviewed about tearing symptoms at a support group meeting in Italy. In Sweden 30 adults primarily from the original thalidomide series were reexamined. In this latter study, a Schirmer test was done at baseline and repeated 5 minutes after eating. Twenty families in Brazil who have children with M?bius sequence were questioned about tearing symptoms and exposure to misoprostol during pregnancy. Results: In the 28 Italian individuals, either "crocodile tears" or lack of emotional tearing was noted in 7 cases. In the thalidomide study, 10 of 30 patients had tearing when eating and 7 had no emotional tearing. Low Schirmer scores or increased tearing after eating was noted in a few asymptomatic individuals. Among the 20 Brazilian children with M?bius sequence, 10 had some tearing abnormality. Conclusion: Congenital anomalous lacrimation is rare but usually associated with Duane syndrome or abduction deficits, as in M?bius sequence and, less frequently, facial nerve palsy. Studies implicate an early insult in development at 4 to 6 weeks. At that time the facial nerve, sixth nerve, and lacrimal nucleus are in close proximity in the embryo.
机译：目的：先天性异常流泪的特征是进食时流泪（“鳄鱼眼泪”），缺乏情感流泪或两者兼而有之。大多数报道的病例与杜安综合征有关。在我们以前的研究中，我们观察到具有沙利度胺胚胎病和M？bius序列的个体出现异常的眼泪。该报告总结了有关该主题的文献，并增加了3项新研究，这些研究提供了有关这种异常情况的信息。方法：在意大利的一个支持小组会议上，对28名具有M？bius序列的人进行了有关撕裂症状的访谈。在瑞典，对30名主要来自原始沙利度胺系列的成年人进行了重新检查。在后一项研究中，在基线进行了一次Schirmer测试，进食后5分钟重复了一次。在巴西，有20个有M？bius序列的孩子的家庭被问到有关流泪症状和怀孕期间米索前列醇的暴露情况。结果：在28名意大利人中，有7例发现“鳄鱼泪”或缺乏情感性泪。在沙利度胺研究中，30名患者中有10名在进食时流泪，而7名没有情感性流泪。在一些无症状的个体中发现低Schirmer评分或进食后流泪的增加。在20名有M？bius序列的巴西儿童中，有10名有一些撕裂异常。结论：先天性异常流泪很少见，但通常与Duane综合征或绑架缺陷有关，如M？bius序列，面神经麻痹少见。研究表明，在4至6周时会对发育进行早期侮辱。那时，面神经，第六神经和泪核在胚胎中非常接近。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号