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Implementation of NICE recommendation for a policy of routine antenatal anti-D prophylaxis: a survey of UK maternity units.

机译:实施NICE推荐的常规产前抗D预防政策:对英国产妇单位的调查。

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The aim of this study was to determine how many UK maternity units have implemented National Institute for Clinical Excellence (NICE) guidance for routine antenatal anti-D prophylaxis (RAADP). In May 2002, the NICE recommended a policy of RAADP for RhD-negative pregnant women. The policy has the potential to reduce maternal sensitization and prevent deaths from haemolytic disease of the foetus and newborn, but implementation entails considerable clinical, financial and organizational challenges. A postal survey of all 324 UK maternity units was completed in 2005.Responses were received from 91% of units (294 of 324). RAADP was offered by 220 of 294 (75%) and in England and Wales 19% of those offered a single-dose regime. At 12% of maternity units, routine paternal blood group testing was offered. For 84% of maternity units, staff education was offered at the time of implementation. Written patient information was provided at 97% of maternity units and 147 of 217 (69%) returned a copy. We received 60 different leaflets. Three years after NICE guidance was issued, one in four maternity units did not offer RAADP. Among those that do offer RAADP, practice with regard to anti-D administration, paternal testing, provision of written information and staff education varied. Unit and clinician level research is required to understand why.
机译:这项研究的目的是确定有多少英国产妇单位实施了美国国家临床卓越研究所(NICE)的常规产前抗D预防(RAADP)指南。在2002年5月,NICE建议对RhD阴性孕妇采取RAADP政策。该政策有可能降低孕产妇的敏感性,并防止因胎儿和新生儿溶血性疾病导致的死亡,但实施该政策带来了巨大的临床,财务和组织挑战。 2005年完成了对英国所有324个生育单位的邮政调查,收到了91%的答复(324个中的294个)。 294例中有220例(75%)提供了RAADP,在英格兰和威尔士,有19%的人提供了单剂量治疗。在12%的产妇单位中,提供了常规的父亲血型检测。在实施时,对84%的产妇单位进行了员工培训。在97%的产妇单位中提供了书面患者信息,并且在217个产妇单位中有147个(69%)返回了副本。我们收到了60张不同的传单。 NICE指南发布三年后,四分之一的产妇未提供RAADP。在提供RAADP的公司中,有关反D管理,父系测试,提供书面信息和员工教育的实践各不相同。需要单位和临床医生进行研究以了解原因。

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