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首页> 外文期刊>Transfusion science >A survey of autologous blood collection and transfusion in Japan in 1997.
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A survey of autologous blood collection and transfusion in Japan in 1997.

机译：1997年在日本进行的自体血液采集和输血调查。

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BACKGROUND: In spite of the fact that autologous blood is safest for a patient to receive, it is not generally appreciated that adverse reactions during donation and transfusion may occur. This study was conducted to assess the state and the risk of autologous blood transfusion in Japan in 1997. STUDY DESIGN AND METHODS: Results of a nation-wide questionnaire-based survey are presented. The questionnaire assessed the number of autologous blood donations, donation procedures, and the adverse reactions associated with donation, preservation, recombination erythropoietin administration and transfusion. RESULTS: Between November 1996 and October 1997, 10,697,000 ml (or 53,485 units, 200 ml = 1 unit) prestorage blood donation were made by 14,200 patients (averages; 1.9 donations/patient, 753 ml/patient, 398 ml/donation). Of these, 87% were transfused to the patients and the remainder were discarded. Using hemodilution and blood salvage intra- or postoperatively some 2,540,000 ml of blood was collected and > 70% of patient-donors received such blood. Adverse reactions were observed with 1.6% (428/26,905) of donations including 6 angina and 2 asthma attacks. There were 63 (0.2%) problems with 28,705 donations and 117 (0.5%) errors/problems reported for 24,929 units transfused; the most frequent problems were clotting on the units and breakage of the bags during storage. Hypotension using hemodilution (3.7%), coagulation (0.9%) or bacterial contamination (0.4%) using salvage were often observed. A 10-20 ml volume of autologous fresh-frozen plasma was transfused to the wrong recipient. CONCLUSION: Autologous blood transfusion accounts for at least 1.1% (2.8% estimated) of the red cell supply in Japan. Errors and adverse reactions are not infrequent in autologous blood programmes. By introducing systematic safety policies, we will be able to make autologous blood transfusion safer.
机译：背景：尽管自体血液对患者而言是最安全的事实，但通常不认识到在捐赠和输血过程中可能发生不良反应。这项研究旨在评估1997年日本的自体输血状况和风险。研究设计与方法：提出了一项基于全国性问卷调查的结果。该问卷评估了自体献血的次数，献血程序以及与献血，保存，重组促红细胞生成素给药和输血相关的不良反应。结果：在1996年11月至1997年10月之间，共有14,200名患者（平均;每人1.9次捐赠，每人753毫升，每人398毫升）捐赠了10,697,000毫升（或53,485单位，200毫升= 1单位）。其中，有87％输给了患者，其余的则被丢弃。在术中或术后使用血液稀释和血液挽救，收集了约254万毫升的血液，超过70％的患者捐赠者接受了这种血液。观察到不良反应，捐赠率为1.6％（428 / 26,905），包括6例心绞痛和2例哮喘发作。报告的24,929单位输血有63（0.2％）个问题，共计28,705笔捐赠和117（0.5％）个错误/问题;最常见的问题是设备上的凝块和存储期间袋子的破损。经常观察到使用血液稀释的低血压（3.7％），凝血（0.9％）或细菌污染（0.4％）的抢救。将10-20毫升体积的自体新鲜冷冻血浆输注到错误的接受者。结论：自体输血至少占日本红细胞供应量的1.1％（估计为2.8％）。在自体血液程序中，错误和不良反应并不罕见。通过引入系统的安全政策，我们将能够使自体输血更加安全。

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