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首页> 外文期刊>Transfusion: The Journal of the American Association of Blood Banks >Frequency and risk factors for donor reactions in an anonymous blood donor survey
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Frequency and risk factors for donor reactions in an anonymous blood donor survey

机译：匿名献血者调查中献血者反应的频率和风险因素

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Background Adverse donor reactions can result in injury and decrease the likelihood of donor return. Reaction reports captured in the blood center's database provide an incomplete picture of reaction rates and risk factors. Study Design and Methods We performed an anonymous survey, mailed to 40,000 donors in 2008, including questions about symptoms, height, weight, sex, and donation status. Reaction rates were compared to those recorded in our database. Possible risk factors were assessed for various reactions. Results The response rate was 45.5%. A total of 32% of first-time and 14% of repeat donors reported having any adverse symptom, most frequently bruising (84.9 per 1000 donors) or feeling faint or weak (66.2 per 1000). Faint reactions were two to eight times higher than reported in our database, although direct comparison was difficult. Younger age, female sex, and first-time donation status were risk factors for systemic and arm symptoms. In females, low estimated blood volume (EBV) was a risk factor for systemic symptoms. Only 51% of donors who consulted an outside physician also called Canadian Blood Services. A total of 10% of first-time donors with reactions found adverse effects information inadequate. Conclusion This study allowed us to collect more information about adverse reactions, including minor symptoms and delayed reactions. Based on our findings of the risk factors and frequency of adverse reactions, we are implementing more stringent EBV criteria for younger donors and providing more detailed information to donors about possible adverse effects and their management.
机译：背景捐助者的不良反应可能会导致伤害并降低捐助者返回的可能性。血液中心数据库中捕获的反应报告提供的反应率和危险因素的图片不完整。研究设计和方法我们进行了一项匿名调查，于2008年邮寄给40,000名捐赠者，其中包括有关症状，身高，体重，性别和捐赠状态的问题。将反应速率与我们数据库中记录的速率进行了比较。评估各种反应的可能危险因素。结果回应率为45.5％。共有32％的首次捐赠者和14％的重复捐赠者报告有任何不良症状，最常见的是瘀​​青（每1000名捐赠者中有84.9人）或感到头晕或虚弱（每1000名中有66.2人）。尽管很难进行直接比较，但微弱的反应比我们数据库中报告的反应高出两到八倍。较年轻的年龄，女性和首次捐赠状态是全身和手臂症状的危险因素。在女性中，低的估计血容量（EBV）是全身症状的危险因素。咨询外部医生的献血者中只有51％也称为加拿大血液服务。共有10％的初次有反应的供体发现不良反应信息不充分。结论这项研究使我们能够收集有关不良反应的更多信息，包括轻微症状和延迟反应。基于对危险因素和不良反应发生频率的发现，我们正在为年轻的捐助者实施更严格的EBV标准，并向捐助者提供有关可能的不良影响及其管理的更详细的信息。

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