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首页> 外文期刊>Turkish Journal of Veterinary and Animal Sciences >Evaluation of various antibiotic treatments in calves with infectious bovine keratoconjunctivitis.
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Evaluation of various antibiotic treatments in calves with infectious bovine keratoconjunctivitis.

机译：牛感染性角膜结膜炎犊牛各种抗生素治疗的评估。

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The purpose of this study was to determine whether subconjunctival administration of enrofloxacin could ameliorate a herd outbreak of infectious bovine keratoconjunctivitis (IBK) and to compare the efficacy of this regimen with the efficacy of subconjunctival administration of a combination of penicillin + streptomycin. The calves were assigned to 1 of 3 groups at the beginning of the study, and were examined 3 times weekly for 4 weeks. Calves in group 1 (n=12) were treated with the subconjunctival administration of a combination of penicillin + streptomycin. This treatment consisted of 3 subconjunctival injections of penicillin + streptomycin every 48 h. Calves in group 2 (n=13) were treated with subconjunctival administration of enrofloxacin, which consisted of 3 subconjunctival injections of enrofloxacin (30 mg) every 48 h. Calves in group 3 (n=13) were not treated and were used as controls. Mean time for healing of corneal ulcers and amelioration of clinical signs was significantly less for calves that received enrofloxacin or penicillin + streptomycin than for the untreated controls. In conclusion, subconjunctival administration of enrofloxacin appears to be an effective method of reducing the severity of a herd outbreak of IBK and may be superior to treatment with penicillin + streptomycin..
机译：这项研究的目的是确定结膜下施用恩诺沙星是否可以缓解牛传染性角膜结膜炎（IBK）的牛群暴发，并将该方案与青霉素+链霉素联合结膜下施用的疗效进行比较。在研究开始时，将小牛分为3组中的1组，每周检查3次，共4周。第1组（n = 12）的小牛经结膜下施用青霉素+链霉素的组合治疗。该治疗包括每48小时3次结膜下注射青霉素+链霉素。结膜下给予恩诺沙星治疗第2组（n = 13）的小牛，该结膜下结膜下注射恩诺沙星（30 mg）每48 h一次。第3组的小牛（n = 13）未治疗，用作对照。与未治疗的对照组相比，接受恩诺沙星或青霉素+链霉素的小牛的角膜溃疡愈合和改善临床体征的平均时间明显更少。总之，结膜下给予恩诺沙星似乎是降低IBK牛群暴发严重程度的有效方法，可能优于青霉素+链霉素的治疗。

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