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首页> 外文期刊>Trends in Plant Science >Emerging role for transcript elongation in plant development
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Emerging role for transcript elongation in plant development

机译:转录本延伸在植物发育中的新兴作用

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Transcript elongation by RNA polymerase II (RNAPII), once regarded as the simple extension of the initiated mRNA, is a complex and highly regulated phase of the transcription cycle. Many factors have been identified that contribute to the dynamic control of the elongation stage of transcription. There are elongation factors that modulate the activity of RNAPII and other factors that facilitate the transcription through chromatin. Recent studies of mutants defective in elongation factors have revealed the importance of proper transcript elongation for the development of higher eukaryotes. Here, the essentials of transcript elongation are briefly summarized to discuss its role in developmental processes.
机译:RNA聚合酶II(RNAPII)的转录延伸曾经被视为起始mRNA的简单延伸,是转录周期的一个复杂且高度受调控的阶段。已经发现许多因素有助于动态控制转录延长阶段。有延伸因子可调节RNAPII的活性,而其他可促进通过染色质转录的因子。对延伸因子有缺陷的突变体的最新研究表明,适当的转录本延伸对于发展高等真核生物很重要。在此,简要总结了转录本延伸的要点,以讨论其在发育过程中的作用。

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