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首页> 外文期刊>Trends in Plant Science >Evolution of plant microRNAs and their targets.
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Evolution of plant microRNAs and their targets.

机译:植物microRNA及其靶标的进化。

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摘要

MicroRNAs (miRNAs) are a specialized class of small silencing RNAs that regulate gene expression. They have a limited phylogenetic distribution among eukaryotes, suggestive of at least two independent origins from an ancestral small RNA-producing pathway. A set of 21 abundantly expressed miRNAs are clearly conserved among the angiosperms; many of these function to regulate transcription factors involved in developmental control. Recent experiments have uncovered a much larger set of weakly expressed, less conserved miRNAs in plants, and this group has provided insights into the origins of miRNAs and their targets. These data have provided a coherent set of hypotheses explaining the birth, selection and death of miRNAs in land plants.
机译:微小RNA(miRNA)是一类特殊的小沉默RNA,可调节基因表达。它们在真核生物中的系统发育分布有限,提示至少有两个来自祖先小RNA产生途径的独立起源。在被子植物中,一组21种高表达的miRNA显然是保守的。这些功能中的许多功能可调节参与发育控制的转录因子。最近的实验发现了植物中大量的弱表达,保守性较低的miRNA,该小组为miRNA的起源及其靶标提供了见识。这些数据提供了一套连贯的假设,解释了陆地植物中miRNA的产生,选择和死亡。

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