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首页> 外文期刊>Trends in Plant Science >Flagellin perception: a paradigm for innate immunity [Review]
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Flagellin perception: a paradigm for innate immunity [Review]

机译：鞭毛蛋白感知：先天免疫的范例[综述]

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摘要

There are surprising similarities between how animals and plants perceive pathogens. In animals, innate immunity is based on the recognition of pathogen-associated molecular patterns. This is mediated by the Toll-like receptor (TLR) family, which rapidly induce the innate immunity response, a first line of defence against infectious disease. Plants have highly sensitive perception systems for general elicitors and they respond to these stimuli with a defence response. One of these general elicitors is flagellin, the main component of the bacterial flagellum. Genetic analysis in Arabidopsis has shown that FLS2, which encodes a receptor-like kinase, is essential for flagellin perception. FLS2 shares homology with the TLR family, and TLR5 is responsible for flagellin perception in mammals.
机译：动植物如何看待病原体之间有惊人的相似之处。在动物中，先天免疫是基于对病原体相关分子模式的识别。这是由Toll样受体（TLR）家族介导的，该家族迅速诱导先天免疫应答，这是抵抗传染病的第一道防线。植物对一般引诱者具有高度敏感的感知系统，它们以防御反应对这些刺激做出反应。这些一般引发剂之一是鞭毛蛋白，它是细菌鞭毛的主要成分。拟南芥的遗传分析表明，编码受体样激酶的FLS2对鞭毛蛋白的感知至关重要。 FLS2与TLR家族具有同源性，而TLR5负责哺乳动物的鞭毛蛋白感知。

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