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首页> 外文期刊>Trends in Plant Science >Arabidopsis PPP family of serine/threonine protein phosphatases: many targets but few engines
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Arabidopsis PPP family of serine/threonine protein phosphatases: many targets but few engines

机译:丝氨酸/苏氨酸蛋白磷酸酶的拟南芥PPP家族:许多靶标但很少引擎

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摘要

The major plant serine/threonine protein phosphatases belong to the phosphoprotein phosphatase (PPP) family. Over the past few years the complement of Arabidopsis thaliana PPP family of catalytic subunits has been cataloged and many regulatory subunits identified. Specific roles for PPPs have been characterized, including roles in auxin and brassinosteroid signaling, in phototropism, in regulating the target of rapamycin pathway, and in cell stress responses. In this review, we provide a framework for understanding the PPP family by exploring the fundamental role of the phosphatase regulatory subunits that drive catalytic engine specificity. Although there are fewer plant protein phosphatases compared with their protein kinase partners, their function is now recognized to be as dynamic and as regulated as that of protein kinases.
机译:植物的主要丝氨酸/苏氨酸蛋白磷酸酶属于磷蛋白磷酸酶(PPP)家族。在过去的几年中,拟南芥PPP催化亚基家族的互补物已被分类并鉴定了许多调控亚基。 PPP的特定作用已被表征,包括在植物生长素和油菜素类固醇信号传导,向光性,调节雷帕霉素途径的靶标以及细胞应激反应中的作用。在这篇综述中,我们通过探索驱动催化引擎特异性的磷酸酶调节亚基的基本作用,为理解PPP系列提供了一个框架。尽管与它们的蛋白激酶伴侣相比,植物蛋白磷酸酶较少,但现已认识到它们的功能与蛋白激酶一样具有动态性和调节性。

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