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Gibberellins and DELLAs: central nodes in growth regulatory networks

机译:赤霉素和DELLAs:增长调控网络中的中心节点

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Gibberellins (GAs) are growth-promoting phytohormones that were crucial in breeding improved semi-dwarf varieties during the green revolution. However, the molecular basis for GA-induced growth stimulation is poorly understood. In this review, we use light-regulated hypocotyl elongation as a case study, combined with a meta-analysis of available transcriptome data, to discuss the role of GAs as central nodes in networks connecting environmental inputs to growth. These networks are highly tissue-specific, with dynamic and rapid regulation that mostly occurs at the protein level, directly affecting the activity and transcription of effectors. New systems biology approaches addressing the role of GAs in growth should take these properties into account, combining tissue-specific interactomics, transcriptomics and modeling, to provide essential knowledge to fuel a second green revolution.
机译:赤霉素(GAs)是促进生长的植物激素,在绿色革命期间对培育改良的半矮品种至关重要。但是,对GA诱导的生长刺激的分子基础了解甚少。在这篇综述中,我们以光调节的下胚轴伸长为例,结合可用转录组数据的荟萃分析,讨论了GA在连接环境输入与生长的网络中作为中心节点的作用。这些网络是高度组织特异性的,具有动态和快速调节功能,主要发生在蛋白质水平,直接影响效应子的活性和转录。解决GA在生长中的作用的新系统生物学方法应将这些特性考虑在内,结合组织特异性相互作用组学,转录组学和建模,以提供必要的知识来推动第二次绿色革命。

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