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首页> 外文期刊>Trends in Plant Science >Agrobacterium tumefaciens as an agent of disease [Review]
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Agrobacterium tumefaciens as an agent of disease [Review]

机译:根癌土壤杆菌作为疾病的病原体[综述]

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摘要

Twenty-six years ago it was found that the common soil bacterium Agrobacterium tumefaciens is capable of extraordinary feats of interkingdom genetic transfer. Since this discovery, A. tumefaciens has served as a model system for the study of type IV bacterial secretory systems, horizontal gene transfer and bacterial-plant signal exchange. It has also been modified for controlled genetic transformation of plants, a core technology of plant molecular biology. These areas have often overshadowed its role as a serious, widespread phytopathogen - the primary driver of the first 80 years of Agrobacteriurn research. Now, the diverse areas of A. tumefaciens research are again converging because new discoveries in transformation biology and the use of A. tumefaciens vectors are allowing the development of novel, effective biotechnology-based strategies for the control of crown gall disease.
机译:二十六年前,人们发现常见的土壤细菌根癌土壤杆菌能够进行非同寻常的遗传遗传转移。自发现以来,根癌农杆菌已成为研究IV型细菌分泌系统,水平基因转移和细菌-植物信号交换的模型系统。还对其进行了修饰,以进行植物的受控遗传转化,这是植物分子生物学的核心技术。这些地区常常掩盖了它作为一种严重的,广泛的植物病原体的作用-这是农杆菌研究最初80年的主要驱动力。现在,根癌农杆菌研究的各个领域再次趋同,因为转化生物学的新发现和根癌农杆菌载体的使用允许开发基于新颖,有效的基于生物技术的冠crown病控制策略。

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