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Estimates of the incidence and prevalence of renal cell carcinoma in Italy in 2002 and projections for the years 2007 and 2012.

机译:意大利2002年肾细胞癌的发病率和患病率估算,以及2007年和2012年的预测。

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AIMS AND BACKGROUND: Data on kidney cancer incidence and prevalence are not available on a national and regional level. We provided estimates of the number of iricident and prevalent cases of kidney and renal cell cancer in Italy overall and in various regions in 2002 and gave projections for the years 2007 and 2012. METHODS: We derived annual numbers of incident cases combining mortality data provided by the World Health Organization and information on relative survival from kidney cancer and we subsequently derived 5-year prevalence by combining incidence with information on survival. We provided different projection estimates for the years 2007 and 2012 for incidence and prevalence, on the basis of various hypothetical scenarios, i.e., stable rates over time or steady falls by 1% per year. RESULTS: In 2002, there were about 8000 incident cases and 26,800 prevalent cases of kidney cancer in Italy. Of these, approximately 6800 and 22,750 were incident and prevalent cases of renal cell cancer, respectively. The most reliable estimate of incident kidney cancer cases in Italy over the period 2007-2012 is likely to range between 7000 and 9000. Of these, between 6000 and 8000 are renal cell cancer cases. The best estimate of prevalence of kidney cancer is between 20,000 and 34,000 cases and that of renal cell cancer between 17,000 and 29,000 cases. CONCLUSIONS: Incidence and prevalence of renal cell cancer are likely to remain approximately stable between 2002 and 2007. Increased diagnostic attention due to widespread use of echography and other diagnostic techniques may, however, lead to earlier detection of kidney neoplasms and consequently to an apparent increase in the incidence of renal cell cancer.
机译:目的和背景:在国家和地区层面尚无关于肾癌发病率和患病率的数据。我们提供了2002年意大利整体和各个地区肾脏和肾细胞癌的同病异病和流行病例的估计数,并提供了2007年和2012年的预测。方法:我们结合每年的死亡率数据得出了每年的事件病例数。世界卫生组织和有关肾癌相对生存的信息,我们随后将发病率与生存信息相结合得出了5年患病率。我们根据各种假设情景,即随着时间推移的稳定比率或每年稳定下降1%,对2007年和2012年的发病率和患病率提供了不同的预测估计。结果:2002年,意大利大约有8000例肾癌事件和26800例肾癌流行病例。其中,分别约有6800和22,750是肾细胞癌的发病和流行病例。在意大利,2007年至2012年期间,最可靠的肾脏肾癌病例估计数可能在7000到9000之间。其中,肾细胞癌病例在6000到8000之间。肾癌患病率的最佳估计是在20,000至34,000例之间,肾细胞癌的患病率在17,000至29,000例之间。结论:肾细胞癌的发病率和患病率在2002年至2007年之间可能保持大致稳定。由于回波描记术和其他诊断技术的广泛使用,对诊断的关注增加,但可能导致早期发现肾脏肿瘤,因此明显增加。在肾细胞癌的发生中。

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