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首页> 外文期刊>Transplant international : >Incidence of minor and major amputations after pancreas/kidney transplantation.
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Incidence of minor and major amputations after pancreas/kidney transplantation.

机译：胰腺/肾脏移植后轻度和大面积截肢的发生率。

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摘要

Among other complications, diabetes mellitus leads to peripheral vascular disease with the risk of limb amputation. This retrospective study analyzed the incidence of amputations after simultaneous pancreas-kidney transplantation (SPK). Between June 1994 and February 2001, 200 SPKs, nine pancreas-after-kidney- (PAK) and one pancreas transplantation alone (PTA) were performed. The overall 5-year patient, pancreas-, and kidney-graft survival rates were 92.4%, 80.2% and 85.6%, respectively. Mean age at transplantation was 38.7 years, mean duration of diabetes was 26.9 years, mean duration of dialysis was 26.7 months. Nineteen (9.5%) patients after SPK (seven female/12 male) underwent 33 amputations, on average 18.7 months after transplantation. Longer duration of dialysis and a previous history of amputation were significant risk factors for an amputation after SPK ( P=0.014, P<0.001). Thus, early referral for SPK before dialysis initiation may be beneficial in preventing amputation.
机译：除其他并发症外，糖尿病还会导致周围血管疾病，并有截肢的危险。这项回顾性研究分析了同时进行胰肾肾移植（SPK）后截肢的发生率。在1994年6月至2001年2月之间，进行了200例SPK，9例肾后肾（PAK）和1例胰腺移植（PTA）。总体5年患者，胰腺和肾移植的存活率分别为92.4％，80.2％和85.6％。移植时的平均年龄为38.7岁，糖尿病的平均持续时间为26.9岁，平均透析的持续时间为26.7个月。 SPK术后有19例（9.5％）患者（7名女性/ 12例男性）接受了33次截肢，平均在移植后18.7个月。较长的透析时间和先前的截肢史是SPK术后截肢的重要危险因素（P = 0.014，P <0.001）。因此，在透析开始前尽早转诊SPK可能有助于预防截肢。

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