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首页> 外文期刊>Carbohydrate Polymers: Scientific and Technological Aspects of Industrially Important Polysaccharides >NMR spectroscopy and imaging studies of pharmaceutical tablets made of starch
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NMR spectroscopy and imaging studies of pharmaceutical tablets made of starch

机译：淀粉制成的药片的NMR光谱学和成像研究

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摘要

Modified polysaccharides such as high amylose starch are used as excipient in controlled drug release technology.Crosslinked high amylose starch is a hydrophilic matrix used for the sustained release of drugs.Tablets using modified hybrid starch as excipient display zero-order release over 2-24 h.A release over 3-4 weeks was observed when the modified starch is used as an implant The use of starch in controlled release system is appealing because it could be easily metabolized in the human body.We review here the use of NMR imaging and solid state ~(13)C spectroscopy in the study of the various factors influencing drug release in such systems.
机译：改性多糖如高直链淀粉用作控释技术中的赋形剂，交联高直链淀粉是用于药物缓释的亲水性基质，使用改性杂种淀粉作为赋形剂的片剂在2-24 hA内零级释放当将改性淀粉用作植入物时，观察到3-4周的释放。在控释系统中使用淀粉很吸引人，因为它很容易在人体中代谢。我们在这里回顾了NMR成像和固态的用法〜 （13）C光谱法研究影响此类系统中药物释放的各种因素。

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