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Importance of widespread gene transfer agent genes in α-proteobacteria

机译:广泛的基因转移剂基因在α-变形杆菌中的重要性

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The gene transfer agent produced by Rhodobacter capsulatus (RcGTA) is a model for several virus-like elements that seem to function solely for mediating gene exchange. Several genes that encode RcGTA are clearly related to bacteriophage genes but the cellular regulatory mechanisms that control RcGTA production indicate that RcGTA is more than just a defective prophage. Genome sequencing projects show that seemingly functional RcGTA-like structural gene clusters are present in many other species of α-proteobacteria, which might also produce RcGTA-like particles. Here, we use the genomic sequence data that are currently available to identify candidate GTA-producing species and propose an evolutionary scheme for RcGTA-like elements in the α-proteobacteria.
机译:荚膜红细菌(RcGTA)产生的基因转移剂是几种病毒样元件的模型,这些病毒样元件似乎仅起中介基因交换的作用。几个编码RcGTA的基因显然与噬菌体基因有关,但是控制RcGTA产生的细胞调节机制表明RcGTA不仅是缺陷的噬菌体。基因组测序项目表明,在许多其他种类的α-变形杆菌中,存在着看似功能性的RcGTA样结构基因簇,它们也可能产生RcGTA样颗粒。在这里,我们使用目前可用的基因组序列数据来识别候选GTA产生物种,并提出了针对α-变形细菌中RcGTA样元件的进化方案。

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