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Vesicular transport across the fungal cell wall

机译:穿过真菌细胞壁的囊泡运输

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Recent findings indicate that fungi use vesicular transport to deliver substances across their cell walls. Fungal vesicles are similar to mammalian exosomes and could originate from cytoplasmic multivesicular bodies. Vesicular transport enables the export of large molecules across the cell wall, and vesicles contain lipids, proteins and polysaccharides, many of which are associated with virulence. Concentration of fungal products in vesicles could increase their efficiency in food acquisition and/or delivering potentially noxious substances to other cells, such as amoebae or phagocytes. The discovery of vesicular transport in fungi opens many new avenues for investigation in basic cell biology and pathogenesis.
机译:最近的发现表明真菌利用囊泡运输将物质跨过细胞壁传递。真菌囊泡类似于哺乳动物的外泌体,可能起源于胞质多囊泡体。囊泡运输使大分子跨细胞壁输出,囊泡中含有脂质,蛋白质和多糖,其中许多与毒力有关。囊泡中真菌产品的浓缩可提高其在食物获取和/或向其他细胞(如变形虫或吞噬细胞)中潜在有害物质的输送效率。真菌中水泡运输的发现为基础细胞生物学和发病机理的研究开辟了许多新途径。

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