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Aspergillus nidulans asexual development: making the most of cellular modules

机译:构巢曲霉无性发育:充分利用细胞模块

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Asexual development in Aspergillus nidulans begins in superficial hyphae as the programmed emergence of successive pseudohyphal modules, collectively known as the conidiophore, and is completed by a layer of specialized cells (phialides) giving rise to chains of aerial spores A discrete number of regulatory factors present in hyphae play different stage-specific roles in pseudohyphal modules, depending on their cellular localization and protein-protein interactions Their multiple roles include the timely activation of a sporulation-specific pathway that governs phialide and spore formation Such functional versatility provides for a new outlook on morphogenetic change and the ways we should study it
机译:构巢曲霉的无性发育始于表层菌丝,这是连续的假菌丝模块(统称为子孢菌)的程序性出现,并由一层专门的细胞(phialides)完成,产生了气生孢子链。存在许多离散的调节因子菌丝在假菌丝模块中发挥不同的阶段特异性作用,具体取决于它们的细胞定位和蛋白质-蛋白质相互作用。它们的多种作用包括适时激活支配phialide和孢子形成的孢子形成特异性途径。这种功能的多样性提供了新的前景。形态发生变化及其研究方法

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