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The rise of model protozoa

机译:模型原生动物的兴起

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It is timely to evaluate the role of protozoa as model organisms given their diversity, abundance and versatility as well as the economic and ethical pressures placed on animal-based experimentation. We first define the term model organism and then examine through examples why protozoa make good models. Our examples reflect major issues including evolution, ecology, population and community biology, disease, the role of organelles, ageing, space travel, toxicity and teaching. We conclude by recognising that although protozoa may in some cases not completely mimic tissue- or whole-animal-level processes, they are extremely flexible and their use should be embraced. Finally, we offer advice on obtaining emergent model protozoa.
机译:考虑到原生动物作为模型有机体的多样性,丰度和多功能性以及基于动物的实验所带来的经济和伦理压力,现在应该对其进行评估。我们首先定义模型生物一词,然后通过示例检查原生动物为何可以创建好的模型。我们的例子反映了主要问题,包括进化,生态,人口和社区生物学,疾病,细胞器的作用,衰老,太空旅行,毒性和教学。我们的结论是,尽管原生动物在某些情况下可能无法完全模仿组织或整个动物水平的过程,但它们具有极高的灵活性,应接受使用。最后,我们提供有关获得紧急模型原生动物的建议。

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