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Host-microbe interactions that facilitate gut colonization by commensal bifidobacteria

机译:通过共生双歧杆菌促进肠道菌落定殖的宿主-微生物相互作用

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摘要

Microorganisms live in a myriad of ecological niches. The human intestine is among the most densely populated environments; here, a multitude of bacteria appear to have co-evolved to impact beneficially upon the health of their human host. The precise molecular mechanisms and signaling pathways employed by commensal bacteria, including those that facilitate colonization and persistence, remain largely unknown despite the perceived positive effects of such host–microbe interactions. In this review we discuss several fascinating relationships between the gastrointestinal tract and commensal bacteria, with particular emphasis on bifidobacteria as a prototypical group of human enteric microorganisms.
机译:微生物生活在无数生态环境中。人体肠道是人口最稠密的环境之一。在这里,许多细菌似乎共同进化,对人类宿主的健康产生了有益的影响。尽管共生细菌使用了精确的分子机制和信号传导途径,包括那些促进定殖和持久性的机制,但尽管它们被认为具有宿主-微生物相互作用的积极作用,但在很大程度上仍然未知。在这篇综述中,我们讨论了胃肠道和共生细菌之间的几种引人入胜的关系,特别强调了双歧杆菌是人类肠道微生物的典型代表。

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