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Fate and effects of veterinary antibiotics in soil

机译:土壤中兽用抗生素的命运和影响

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摘要

Large amounts of veterinary antibiotics are applied worldwide to farm animals and reach agricultural fields by manure fertilization, where they might lead to an increased abundance and transferability of antibiotic-resistance determinants. In this review we discuss recent advances, limitations, and research needs in determining the fate of veterinary antibiotics and resistant bacteria applied with manure to soil, and their effects on the structure and function of soil microbial communities in bulk soils and the rhizosphere. The increased abundance and mobilization of antibiotic-resistance genes (ARGs) might contribute to the emergence of multi-resistant human pathogens that increasingly threaten the successful antibiotic treatment of bacterial infections
机译:在世界范围内,大量的兽用抗生素被用于农场动物,并通过肥料施肥进入农田,这可能导致抗生素抗性决定簇的丰度和可转移性增加。在这篇综述中,我们讨论了确定肥料中施用的兽用抗生素和抗药性细菌的命运及其对散装土壤和根际土壤微生物群落结构和功能的影响的最新进展,局限性和研究需求。抗生素抗性基因(ARG)的丰度和动员性增加可能会导致多重耐药的人类病原体的出现,这些病原体越来越多地威胁对细菌感染的成功抗生素治疗

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