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Global dissemination of the Mycobacterium tuberculosis W-Beijing family strains

机译:结核分枝杆菌W-北京家族菌株的全球传播

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摘要

A large, genetically related group of Mycobacterium tuberculosis strains, variously called W or Beijing, is distinguished by specific molecular markers and referred to as the W-Beijing family strains. Molecular epidemiological studies suggest that these strains are highly prevalent throughout Asia and the countries of the former Soviet Union and they have also been reported in several other geographical regions, including North America. Although the spread of W-Beijing family strains in diverse populations is well documented, the underlying host-pathogen factors accounting for their continued dissemination and burden of disease have yet to be determined.
机译:一大批与遗传相关的结核分枝杆菌菌株,分别称为W或Beijing,通过特定的分子标记来区分,被称为W-Beijing家族菌株。分子流行病学研究表明,这些菌株在亚洲和前苏联国家中非常普遍,并且在包括北美在内的其他几个地理区域也有报道。尽管W-Beijing家庭菌株在不同人群中的传播已有充分文献记载,但尚需确定导致其继续传播和疾病负担的潜在宿主-病原体因素。

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