Transforming growth factor #beta# in infectious disease: always there for the host and the pathogen

David R. Fitzpatrick; Helle Bielefeldt-Ohmann

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Transforming growth factor #beta# in infectious disease: always there for the host and the pathogen

机译：传染病中转化生长因子＃beta＃：宿主和病原体始终存在

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At the portals of pathogen entry, there are pools of the latent form of a potent cytokine, transforming growth factor #beta# (TGF-#beta#). Many infections activate these pools and stimulate further TGF-#beta# expression. As well as potent immunomodulation, activated TGF-#beta# might have important effects on pathogen entry, replication, persistence, latency and oncogenesis.

机译：在病原体进入的门户，有潜在形式的有效细胞因子池，可转化生长因子＃beta＃（TGF-＃beta＃）。许多感染会激活这些库并刺激进一步的TGF-βbeta＃表达。除有效的免疫调节外，活化的TGF-βbeta＃可能对病原体的进入，复制，持久性，潜伏期和致癌作用也有重要影响。

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《Trends in Microbiology》 |1999年第6期|共5页
作者
David R. Fitzpatrick; Helle Bielefeldt-Ohmann;
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原文格式 PDF
正文语种 eng
中图分类微生物学;
关键词
infectious disease; transforming growth factor; beta; infectious agents; hosts;

机译：传染病;转化生长因子;β;传染原;宿主;

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专利

1. Transforming growth factor #beta# in infectious disease: always there for the host and the pathogen [J] . David R. Fitzpatrick, Helle Bielefeldt-Ohmann Trends in Microbiology . 1999,第6期

机译：传染病中转化生长因子＃beta＃：宿主和病原体始终存在
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3. A global study of pathogens and host risk factors associated with infectious gastrointestinal disease in returned international travellers. [J] . Swaminathan A, Torresi J, Schlagenhauf P Journal of Infection . 2009,第1期

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5. Host-Pathogen Dynamics in a Changing Environment: Susceptibility of Amphibians to an Emerging Infectious Disease [D] . Searle, Catherine L. 2011

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6. Computational Tools for Investigating Pathogen Pathogen-Host Interaction and Infectious Disease [O] . Jialiang Yang, Bo Liao, Jianqiang Ye, 2018

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7. Computational Tools for Investigating Pathogen, Pathogen-Host Interaction, and Infectious Disease [O] . Jialiang Yang, Bo Liao, Jianqiang Ye, 2018

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Transforming growth factor #beta# in infectious disease: always there for the host and the pathogen

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