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A marriage of bacteriology with cell biology results in twin arginines

机译:细菌学与细胞生物学的结合产生了双精氨酸

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摘要

The Tat apparatus is a remarkable molecular machine required for the transmembrane translocation of folded proteins. Recent studies have identified jellyfish green fluorescent protein as an excellent reporter protein for the bacterial Tat pathway. Although the genetics of the Tat system are reasonably well-defined in Escherichia coli, the utilization of heterologous proteins as transport substrates promises to facilitate further mechanistic and structural characterization of this system.
机译:Tat设备是折叠蛋白跨膜易位所需的杰出分子机器。最近的研究已将水母绿色荧光蛋白鉴定为细菌Tat途径的优秀报告蛋白。尽管Tat系统的遗传学在大肠杆菌中定义合理,但利用异源蛋白作为转运底物有望促进该系统的进一步机械和结构表征。

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