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Emerging Technologies for Gut Microbiome Research

机译:肠道微生物组研究的新兴技术

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Understanding the importance of the gut microbiome on modulation of host health has become a subject of great interest for researchers across disciplines. As an intrinsically multidisciplinary field, microbiome research has been able to reap the benefits of technological advancements in systems and synthetic biology, biomaterials engineering, and traditional microbiology. Gut microbiome research has been revolutionized by high-throughput sequencing technology, permitting compositional and functional analyses that were previously an unrealistic undertaking. Emerging technologies, including engineered organoids derived from human stem cells, high-throughput culturing, and microfluidics assays allowing for the introduction of novel approaches, will improve the efficiency and quality of microbiome research. Here, we discuss emerging technologies and their potential impact on gut microbiome studies.
机译:了解肠道微生物组对调节宿主健康的重要性已成为跨学科研究人员的极大兴趣。作为一个内在的多学科领域,微生物组研究已经能够从系统和合成生物学,生物材料工程和传统微生物学的技术进步中获得收益。肠道微生物组研究已通过高通量测序技术进行了革新,允许进行以前不切实际的成分和功能分析。新兴技术,包括衍生自人类干细胞的工程化类器官,高通量培养和允许引入新方法的微流控测定,将提高微生物组研究的效率和质量。在这里,我们讨论新兴技术及其对肠道微生物组研究的潜在影响。

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