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首页> 外文期刊>Tropical Medicine and International Health: TM and IH >Pneumonia among young infants in rural Southeast Asia (Bohol Island, Philippines).
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Pneumonia among young infants in rural Southeast Asia (Bohol Island, Philippines).

机译：东南亚农村地区（菲律宾薄荷岛）幼儿的肺炎。

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OBJECTIVE: To develop a clinical algorithm that can be used to identify pneumonia deaths in young infants in developing countries and estimate the disease burden in this population. PATIENTS AND METHODS: Infants younger than 60 days hospitalized with signs of severe pneumonia who underwent clinical, microbiologic and radiological evaluation were the subjects. Stepwise logistic regression and subtractive iterative process were used to derive the algorithm. RESULTS: Three-hundred and one infants had either clinical or radiographic pneumonia. The case fatality rate for 185 infants with radiographic pneumonia was 21%vs. 5% for clinical pneumonia. Age below 7 days was associated with an increased risk of dying. Among 7- to 59-day-old infants, poor feeding, cyanosis and absence of crackles were predictors of death from pneumonia. Using logistic regression, an algorithm consisting of any one of three clinical signs (cyanosis, poor feeding and abnormally sleepy) was developed in infants aged 7-59 days; 80% of deaths and 50% of those with radiographic pneumonia have at least one of these signs. It performed better than both the WHO case management algorithm and the IMCI algorithm. CONCLUSION: Radiographic pneumonia is a common and serious infection among infants below 2 months old in the Philippines. Cyanosis, poor feeding and abnormal sleepiness are simple signs that can be used by health workers to identify seriously ill infants who are most likely to die from pneumonia.
机译：目的：开发一种临床算法，可用于识别发展中国家幼儿中的肺炎死亡并估算该人群的疾病负担。患者和方法：对象为60天内住院的有严重肺炎迹象的婴儿，这些婴儿经过临床，微生物学和放射学评估。使用逐步逻辑回归和减法迭代过程来推导该算法。结果：301例患儿患有临床或影像学肺炎。 185例放射性肺炎婴儿的病死率为21％vs。 5％为临床肺炎。低于7天的年龄与死亡风险增加相关。在7到59天的婴儿中，喂养不足，发和无crack裂是肺炎死亡的预兆。使用逻辑回归，开发了一种由三种临床症状（紫osis，喂养不良和异常困倦）中的任何一种组成的算法，适用于7-59天的婴儿;至少80％的死亡和50％的放射性肺炎患者具有以下至少一种体征。它的表现优于WHO病例管理算法和IMCI算法。结论：放射线性肺炎是菲律宾2个月以下婴儿的常见和严重感染。发yan，进食不佳和异常嗜睡是简单的迹象，医护人员可以使用它们来识别最可能死于肺炎的重病婴儿。

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