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首页> 外文期刊>Tropical Medicine and International Health: TM and IH >Seroprevalence of varicella-zoster virus infection in children from Cochabamba: Tropical or temperate pattern?
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Seroprevalence of varicella-zoster virus infection in children from Cochabamba: Tropical or temperate pattern?

机译：科恰班巴儿童的水痘-带状疱疹病毒感染的血清流行：热带还是温带模式？

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Objectives: To determine the seroprevalence of varicella-zoster viral (VZV) infections in schoolchildren from the Cochabamba region (Bolivia), and its association with socio-demographic variables, socio-economic status and geographical location. Methods: Seroepidemiological survey (n = 436) on VZV of schoolchildren living in the Cochabamba region of Bolivia in 2010. An ELISA test was used to measure varicella antibodies. Parents or guardians completed a questionnaire regarding socio-demographic information (age, gender, living area, parental educational level, presence of siblings and number of family members in the household), and a blood sample was collected from each child to check for VZV antibodies. A descriptive and bivariate analysis was performed. Results: The global prevalence of VZV was 78.2% (95% CI 74.3-82.1). It was higher in females (82.1%), pre-adolescents (aged 10.1-13 years: 81.4%) and adolescents (aged >13 years: 80.2%), in children with less well-educated parents (81.3% to 81.6%), in warmer municipalities (81.4% to 82.2%), in rural areas (80.0%), in children with siblings (80.1%), those who although the latter association was not statistically significant. Conclusions: The prevalence of VZV infection in childhood was relatively high for a tropical country, and much closer to that of temperate countries prior to the introduction of varicella vaccine into vaccination programmes. ? 2012 Blackwell Publishing Ltd.
机译：目的：确定来自科恰班巴地区（玻利维亚）的学童的水痘带状疱疹病毒（VZV）感染的血清流行率，及其与社会人口学变量，社会经济地位和地理位置的关系。方法：2010年对玻利维亚科恰班巴地区小学生的VZV进行了血清流行病学调查（n = 436）。采用ELISA试验测量水痘抗体。父母或监护人填写了有关社会人口统计学信息的问卷（年龄，性别，居住地区，父母的受教育程度，兄弟姐妹的存在和家庭成员的数量），并从每个孩子那里采集了血液样本以检查VZV抗体。进行描述性和双变量分析。结果：VZV的全球患病率为78.2％（95％CI 74.3-82.1）。女性（82.1％），青春期前（10.1-13岁：81.4％）和青少年（13岁以上：80.2％），父母教育程度较低的儿童（81.3％至81.6％）更高。在较热的城市（81.4％至82.2％），农村地区（80.0％），有兄弟姐妹的儿童（80.1％）中，尽管后者之间的联系没有统计学意义。结论：在热带国家，儿童期VZV感染的患病率相对较高，在将水痘疫苗引入疫苗接种计划之前，与温带国家的患病率非常接近。 ？ 2012布莱克威尔出版有限公司

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