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首页> 外文期刊>Tropical Animal Health and Production >Seroprevalence of brucellosis in yaks (Poephagus grunniens) in India and evaluation of protective immunity to S19 vaccine
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Seroprevalence of brucellosis in yaks (Poephagus grunniens) in India and evaluation of protective immunity to S19 vaccine

机译：印度牛布氏杆菌病的血清流行率和对S19疫苗的保护性免疫的评估

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摘要

The present study was carried out to explore the seroprevalence of brucellosis in yaks of North-Eastern hilly yak tracts of Arunachal Pradesh, India. Of 374 animals tested, 23.79, 21.11 and 18.98% were found positive for brucellosis using avidin-biotin ELISA (AB-ELISA), Rose-Bengal plate test (RBPT) and standard tube-agglutination test (STAT), respectively. The relative sensitivity and specificity for STAT were 79.77 and 100%, respectively and the same for RBPT were 88.76 and 100%, respectively in comparison to AB-ELISA. The alarming prevalence as recorded was highest among the yak cows (31.42%) followed by heifers (23.85%) and bulls (8.88%). The immune response in yaks following standard dose of calfhood vaccination with Brucella abortus strain 19 vaccine showed that protective antibody level persisted up to 210 days. This is the first report from India on prevalence of brucellosis and immunization with B abortus strain 19 vaccine in yaks. The present investigation would be a valuable guideline for future control measure and eradication programme of brucellosis in yaks.
机译：本研究旨在探讨印度阿鲁纳恰尔邦东北丘陵牛区ak牛中布鲁氏菌病的血清阳性率。在使用抗生物素蛋白生物素ELISA（AB-ELISA），玫瑰孟加拉平板试验（RBPT）和标准管凝集试验（STAT）的374只动物中，布鲁氏菌病阳性的比例分别为23.79％，21.11％和18.98％。与AB-ELISA相比，STAT的相对灵敏度和特异性分别为79.77和100％，RBPT的相对灵敏度和特异性分别为88.76和100％。记录的惊人流行率在牛中最高（31.42％），其次是小母牛（23.85％）和公牛（8.88％）。在标准剂量的小肠流产布鲁氏菌19株小牛疫苗接种后，牛的免疫反应表明保护性抗体水平持续了210天。这是印度关于布鲁氏菌病流行率和with牛B流产19株疫苗免疫的首次报道。本研究将为future牛布鲁氏菌病的未来控制措施和根除计划提供有价值的指导。

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