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首页> 外文期刊>Tropical Animal Health and Production >Heat shock protein 70, oxidative stress, and antioxidant status in periparturient crossbred cows supplemented with alpha -tocopherol acetate.
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Heat shock protein 70, oxidative stress, and antioxidant status in periparturient crossbred cows supplemented with alpha -tocopherol acetate.

机译：补充α-生育酚乙酸酯的围产期杂交奶牛的热休克蛋白70，氧化应激和抗氧化状态。

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摘要

The study was conducted to investigating the effect of alpha -tocopherol acetate on heat shock protein 70 (Hsp70), oxidative stress, and antioxidant status during periparturient period in medium body condition score crossbred cows. Twenty crossbred Karan Fries cows with confirmed pregnancy were selected 2 months before expected date of calving. The cows were randomly distributed in to two groups: 10 cows were kept as control and 10 were supplemented with alpha -tocopherol acetate during dry period for 2 months. Blood samples were collected at -20, -10, -5, 0, 5, 10, and 20 days in relation to the expected date of calving. Superoxide dismutase, catalase, and total immunoglobulin were significantly higher (P<0.01) in treatment as compared to control cows. Heat shock protein 70 and thiobarbituric acid reactive substance levels were significantly lower (P<0.01) in the treatment cows than their counterpart. Treatment with alpha -tocopherol acetate during dry period resulted in reduced oxidative stress, heat shock protein Hsp70 levels, improved antioxidant, and improved immunity status indicating beneficial effect of alpha -tocopherol acetate treatment.
机译：该研究旨在调查中度体况评分杂交母牛围产期α-生育酚乙酸酯对热休克蛋白70（Hsp70），氧化应激和抗氧化状态的影响。在预期产犊日期前两个月，选择了20头经证实怀孕的杂交Karan Fries母牛。将母牛随机分为两组：将10头母牛作为对照，并在10个月的干燥期中补充10％的α-生育酚乙酸酯。相对于产犊的预期日期，在-20，-10，-5、0、5、10和20天收集血样。与对照牛相比，治疗中的超氧化物歧化酶，过氧化氢酶和总免疫球蛋白明显更高（P <0.01）。处理奶牛的热休克蛋白70和硫代巴比妥酸反应性物质水平显着低于同龄奶牛（P <0.01）。在干燥期间用乙酸α-生育酚处理可降低氧化应激，降低热休克蛋白Hsp70的水平，改善抗氧化剂，并改善免疫状态，表明乙酸α-生育酚处理具有有益作用。

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