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Effect of intravaginal fluorogestone acetate sponges on prolactin levels of Damascus-local cross breed goats

机译:阴道内氟代醋酸石海绵对大马士革本地杂交品种催乳素水平的影响

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The effect of intravaginal fluorogestone acetate (FGA) sponges on prolactin levels (PRL) and correlations between PRL and milk somatic cell count (SCC) and steroid hormones levels of Damascus-local cross goats during transitional period to anestrous were investigated in this study. Fifty-six goats were assigned to three groups. Group 1 (FGA, n=19) was treated with 40 mg FGA and equine chorionic gonadotropin (600 IU, i.m.) at time of sponge withdrawal (day 0). Group 2 (FGA-PGF; n=19) was treated similar to group 1 but was also injected with dinoprost tromethamine (naturally occurring PGF(2 alpha)) (10 mg, i.m.) on day 0. Control goats (n=18) were left untreated. On day 0, five fertile bucks were turned in with all goats. Milk and blood samples were collected on days -13 (day of sponge insertion), -6, 0, 1, 2, 7, 13, and 20. Prolactin levels were at lowest values on day -13 of the study and increased (p0.05) from day -6 to day 20 in all groups. A significant positive correlation (p0.05) between PRL and progesterone and between PRL and estradiol levels was found in this study. No significant correlation was found between PRL and SCC of all groups during the study except on days 2 and 20 where PRL levels were correlated (p0.05) with SCC of left udder halves of FGA group. In conclusion, estrus induction with FGA resulted in significant increase in PRL. A positive correlation was found between PRL and steroid hormones, but there was no correlation between PRL and goat milk SCC.
机译:在这项研究中,研究了阴道内氟代氟乙酸石(FGA)海绵对催乳素水平(PRL)的影响以及大马士革本地杂交山羊的PRL与乳体细胞计数(SCC)和类固醇激素水平之间的相关性。五十六只山羊被分为三组。在取出海绵时(第0天),用40mg FGA和马绒毛膜促性腺激素(600IU,i.m。)处理组1(FGA,n = 19)。第2组(FGA-PGF; n = 19)的治疗与第1组相似,但在第0天也注射了狄诺前列酮三甲胺(天然存在的PGF(2 alpha))(10 mg,im)。对照山羊(n = 18)不予治疗。在第0天,向所有山羊交出5头可育雄鹿。在第-13天(海绵插入日),-6、0、1、2、7、13和20天收集牛奶和血液样本。催乳素水平在研究的第-13天处于最低值,并且升高(p所有组从-6天到20天均<0.05)。在这项研究中发现PRL和孕激素之间以及PRL和雌二醇水平之间存在显着的正相关(p <0.05)。在研究期间,除第2天和第20天PRL水平与FGA组左半乳的SCC相关(p <0.05)外,所有组的PRL和SCC之间均未发现显着相关性。总之,FGA诱导发情导致PRL显着增加。 PRL与类固醇激素之间呈正相关,但PRL与山羊奶SCC之间无相关性。

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