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首页> 外文期刊>Tropical Animal Health and Production >Molecular epidemiology of Newcastle disease viruses in Vietnam.
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Molecular epidemiology of Newcastle disease viruses in Vietnam.

机译：越南新城疫病毒的分子流行病学。

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摘要

Newcastle disease virus (NDV) causes significant economic losses to the poultry industry in Southeast Asia. In the present study, 12 field isolates of NDV were recovered from dead village chickens in Vietnam between 2007 and 2012, and were characterized. All the field isolates were classified as velogenic. Based on the sequence analysis of the F variable region, two distinct genetic groups (Vietnam genetic groups G1 and G2) were recognized. Phylogenetic analysis revealed that all the 12 field isolates fell into the class II genotype VII cluster. Ten of the field isolates, classified as Vietnam genetic group G1, were closely related to VIIh viruses that had been isolated from Indonesia, Malaysia, and Cambodia since the mid-2000s, while the other two field isolates, of Vietnam genetic group G2, clustered with VIId viruses, which were predominantly circulating in China and Far East Asia. Our results indicate that genotype VII viruses, especially VIIh viruses, are predominantly responsible for the recent epizootic of the disease in Vietnam.
机译：新城疫病毒（NDV）对东南亚的家禽业造成重大经济损失。在本研究中，从2007年至2012年期间从越南的死村鸡中回收了12株NDV野外分离株，并进行了鉴定。所有的野外分离株都被分类为velogenic。根据F可变区的序列分析，识别出两个不同的遗传组（越南遗传组G1和G2）。系统发育分析表明，所有12个田间分离株都属于II类基因型VII簇。自2000年代中期以来，从印度尼西亚，马来西亚和柬埔寨分离出的VIIh病毒中，有10个被称为越南G1基因组的野外分离株与VIIh病毒密切相关，而越南基因G2的另外两个野外分离株则聚在一起带有VIId病毒，这些病毒主要在中国和远东亚洲传播。我们的结果表明，基因型VII病毒，尤其是VIIh病毒，主要是越南最近对该疾病的流行的原因。

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