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首页> 外文期刊>Tropical Animal Health and Production >In vivo effect of selected medicinal plants against gastrointestinal nematodes of sheep
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In vivo effect of selected medicinal plants against gastrointestinal nematodes of sheep

机译：精选药用植物对绵羊胃肠道线虫的体内作用

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Nematode resistance to anthelmintic drugs affects small ruminant production globally. This study evaluated in vivo effects of five plant extracts as alternative nematode treatments. Animals were divided into six groups. Each group was randomly assigned a treatment: Abamectin and Praziquantel (CAP) (positive Control), ethanol extracts of Ananas comosus (AC), Aloe ferox (AF), Allium sativum (AS), Lespedeza cuneata (LC) and Warburgia salutaris (WS). These were applied as an oral dose (100 mg kg(-1) BW), one dose per week per sheep for 42 days (Phase 1). From day 42 sheep were orally dosed for 3 consecutive days with the same treatments in the same groups (Phase 2). Rectal faecal samples were taken every 7 days up to day 63. Eggs per gram of faeces were counted in individual rectal samples, L-3 larval stage was counted in faecal cultures, with four replicates per group. For plant extracts, EPG decreased (P < 0.001) with time and efficacy of plant increased (P < 0.001) with time. Ananas comosus and L. cuneata treatments had the highest efficacies of 58 % and 61 %, respectively, in Phase 1; and 77 % and 81 %, respectively, in Phase 2. Continuous treatment with these plants could further reduce nematode parasites and improve host health.
机译：线虫对驱虫药的抗药性影响全球范围内的小反刍动物生产。这项研究评估了五种植物提取物作为替代线虫治疗方法的体内作用。将动物分为六组。每组被随机分配一种治疗方法：阿维菌素和吡喹酮（CAP）（阳性对照），凤梨（AC），乙醇芦荟（AF），大蒜（AS），Lespedeza cuneata（LC）和Warburgia salutaris（WS）的乙醇提取物。 ）。这些剂量为口服剂量（100 mg kg（-1）BW），每只羊每周一次，持续42天（阶段1）。从第42天起，在相同组中连续3天对绵羊进行口服剂量的相同处理（第2阶段）。直到第63天，每7天采集一次直肠粪便样品。在每份直肠样品中对每克粪便中的卵进行计数，在粪便培养物中对L-3幼虫期进行计数，每组重复四次。对于植物提取物，EPG随时间降低（P <0.001），植物功效随时间增加（P <0.001）。在第一阶段中，Ananas comosus和L. cuneata处理的最高效率分别为58％和61％。在阶段2中分别为77％和81％。用这些植物进行连续处理可以进一步减少线虫寄生虫并改善宿主健康。

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