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首页> 外文期刊>Trends in Neurosciences >The albino retina: an abnormality that provides insight into normal retinal development.
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The albino retina: an abnormality that provides insight into normal retinal development.

机译:白化病视网膜:一种异常现象,可以洞悉正常的视网膜发育。

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摘要

Albino mammals have specific deficits in their retinae and in the pattern of decussation at their optic chiasm, demonstrating that a melanin-related agent is crucial for normal development of the visual system. Although much attention has been paid to chiasmatic abnormality over the past 30 years, little progress has been made in understanding the abnormality. There has now been a shift of attention towards an analysis of the developing albino retina, which is providing significant advances in our understanding of the role played by this melanin-related agent. It is now possible to identify one candidate substance that emanates from the synthetic pathway of melanin that plays a key role in regulating retinal development.
机译:白化病哺乳动物的视网膜和视交叉病变处有特定的缺陷,表明黑色素相关药物对视觉系统的正常发育至关重要。尽管在过去的30年中,人们对Chiasmatic异常给予了极大的关注,但是在了解异常方面进展甚微。现在,人们的注意力转向了对发展中的白化病视网膜的分析,这为我们对这种黑色素相关药物所起的作用的理解提供了重要进展。现在有可能鉴定出一种来自黑色素合成途径的候选物质,该物质在调节视网膜发育中起关键作用。

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