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首页> 外文期刊>Value in health: the journal of the International Society for Pharmacoeconomics and Outcomes Research >Estimating Quality-Adjusted Life-Year Loss Due to Noncommunicable Diseases in Korean Adults through to the Year 2040
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Estimating Quality-Adjusted Life-Year Loss Due to Noncommunicable Diseases in Korean Adults through to the Year 2040

机译：估算直至2040年韩国成年人因非传染性疾病而进行的质量调整后的终生损失

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Objectives: To estimate the loss in quality-adjusted life-years (QALYs) in Korean adults due to 13 noncommunicable diseases (NCDs) in 2010 and predict changes in QALY loss through to the year 2040. Methods: Thirteen NCDs (hypertension, diabetes mellitus, hyperlipidemia, stroke, myocardial infarction, angina, arthritis, osteoporosis, asthma, allergic rhinitis, atopic dermatitis, cataract, and depression) were selected from the Korean Community Health Survey 2010. The Euro-Qol five-dimensional questionnaire index from the Korean Community Health Survey 2010 and the Korean valuation set were used to estimate utility weights according to sex, age, and disease. Morbidity data were also obtained from the Korean Community Health Survey 2010. Mortality data according to disease and life expectancy were retrieved from the Korean Statistical Information Service. To predict future QALY loss, future population projection data from the Korean Statistical Information Service were used as substitutes for 2010 population size. Results: Among the assessed 13 NCDs, the largest total QALY loss was for hypertension (513,113 QALYs; units are omitted hereafter), followed by arthritis (509,317) and stroke (431,049). The largest QALY loss due to mortality was stroke (306,733), whereas the largest QALY loss due to morbidity was arthritis (502,513). By applying the middle estimate of future population, the largest increase in total QALY loss between 2010 and 2040 was for hypertension (840,582), followed by stroke (719,076) and diabetes mellitus (474,607). Conclusions: Hypertension, arthritis, and stroke are important in terms of total QALY loss, which will continuous to increase because of aging. These results could be used to develop cost-effective interventions that reduce the burden of NCDs. (C) 2015 Published by Elsevier Inc. on behalf of International Society for Pharmacoeconomics and Outcomes Research (ISPOR).
机译：目的：估计2010年由于13种非传染性疾病（NCD）导致的韩国成年人的质量调整生命年（QALYs）损失，并预测到2040年QALY损失的变化。方法：13种NCD（高血压，糖尿病） ，高脂血症，中风，心肌梗塞，心绞痛，关节炎，骨质疏松症，哮喘，过敏性鼻炎，特应性皮炎，白内障和抑郁症）均选自2010年韩国社区健康调查。韩国社区的Euro-Qol五维问卷指数根据性别，年龄和疾病，使用《 2010年健康调查》和韩国的估值集来估算公用事业权重。死亡率数据也来自2010年韩国社区健康调查。根据疾病和预期寿命的死亡率数据可从韩国统计信息服务局获取。为了预测未来的QALY损失，韩国统计信息服务局的未来人口预测数据被用来替代2010年的人口规模。结果：在评估的13个NCD中，总的QALY损失最大的是高血压（513,113 QALYs;此后省略单位），其次是关节炎（509,317）和中风（431,049）。由于死亡率而导致的最大QALY损失是中风（306,733），而由于发病率而导致的最大的QALY损失是关节炎（502,513）。通过对未来人口的中间估计，2010年至2040年期间，QALY总体损失的最大增加是高血压（840,582），其次是中风（719,076）和糖尿病（474,607）。结论：就总QALY损失而言，高血压，关节炎和中风很重要，而QALY的损失将随着年龄的增长而持续增加。这些结果可用于制定具有成本效益的干预措施，减轻非传染性疾病的负担。 （C）2015年由Elsevier Inc.代表国际药物经济学和结果研究学会（ISPOR）出版。

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