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Two cases of bradyarrhythmia and hypotension after extradural injections in dogs

机译:硬膜外注射后狗的心律失常和低血压2例

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Two healthy obese, seven-year-old, female Rottweilers weighing 40 and 57 kg were submitted for cranial cruciate repair. They were premedicated with intravenous methadone (0.1 mg kgp#) and acepromazine (0.01 and 0.02 mg kgp#). Anesthesia was induced with propofol (3.6 and 2.5 mg kgp#) and maintained with isoflurane in oxygen using a circle breathing system. The dogs were placed in sternal recumbency and epidural injection of lidocaine/bupivacaine or lidocaine/bupivacaine/morphine (0.2 mL/kg, 8 and 11 mL) was carried out over 1.5 and 4 minutes. Epidural pressures were 79 and 72 mmHg at the end of the injections. The first dog's heart rate decreased from 80 to 65 beats minutep# with a second degree atrioventricular (AV) block. The arterial pressure decreased from 100 to 50 mmHg. These responded to atropine (0.01 mg kgp# IV). The second dog's heart rate decreased from 120 to 60 beats minutep# while arterial pressure decreased from 72 to 38 mmHg. No treatment was given and heart rate and arterial blood pressure returned to acceptable ranges. These cases suggest that large increases in epidural pressure may cause significant cardiovascular effects. This may be avoided by using lower volumes and discontinuing injection if significant back pressure is detected.
机译:提交了两名体重分别为40和57公斤的健康肥胖,七岁的女性Rottweilers进行颅骨交叉修复。他们接受了静脉美沙酮(0.1 mg kgp#)和醋丙嗪(0.01和0.02 mg kgp#)的药物治疗。用丙泊酚(3.6和2.5 mg kgp#)诱导麻醉,并使用循环呼吸系统在氧气中用异氟烷维持麻醉。将狗置于胸骨卧位,并在1.5和4分钟内硬膜外注射利多卡因/布比卡因或利多卡因/布比卡因/吗啡(0.2 mL / kg,8和11 mL)。注射结束时硬膜外压力分别为79和72 mmHg。第一只狗的心率从80次/分降至65次/分,伴有第二度房室(AV)阻滞。动脉压从100毫米汞柱降至50毫米汞柱。这些对阿托品有反应(0.01 mg kgp#IV)。第二只狗的心率从120次/分降低到60次/分,而动脉压从72毫米汞柱降低到38毫米汞柱。没有进行任何治疗,心率和动脉血压恢复到可接受的范围。这些病例表明,硬膜外压力的大幅度升高可能会导致明显的心血管疾病。如果检测到明显的背压,可以通过使用较小的体积并停止进样来避免这种情况。

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