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首页> 外文期刊>Turkish Journal of Fisheries & Aquatic Sciences >Effects of humic acid on liver and kidney toxicity induced by cadmium in brown trout (Salmo trutta fario, L).
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Effects of humic acid on liver and kidney toxicity induced by cadmium in brown trout (Salmo trutta fario, L).

机译：腐殖酸对褐鳟中镉诱导的肝肾毒性的影响（Salmo trutta fario，L​​）。

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摘要

This study was conducted to determine the histopathological and biochemical effects of humic acid on cadmium stress in liver and kidney tissues of Salmo trutta fario, L. The fish were treated in four groups as follows and were exposed to chemicals for 7 days: control (C), cadmium (2 ppm) (Cd), humic acid (5 ppm) (HA) and humic acid+cadmium (Cd+HA). At the end of the experimental period, liver and kidney samples were taken from all fish for histopathological examination and determination of antioxidant enzyme (glutathione peroxidase, superoxide dismutase) and malondialdehyde (MDA) levels. Activity of GPx and SOD in the tissues of fish exposed to the stress of Cd was significantly lower than the control groups (P<0.05). MDA level increased (P<0.05) in cadmium exposed groups, whereas fish receiving cadmium with humic acid returned to normal MDA levels in the liver. The cadmium-induced histopathological alterations were also decreased with humic acid. These results suggest that humic acid may mediate cadmium toxicity.
机译：本研究旨在确定腐殖酸对L.Salmo trutta fario，L​​肝和肾组织中镉胁迫的组织病理学和生化影响。将鱼按以下四组进行处理，并暴露于化学药品中7天：对照（C ），镉（2 ppm）（Cd），腐殖酸（5 ppm）（HA）和腐殖酸+镉（Cd + HA）。在实验期结束时，从所有鱼类中采集肝脏和肾脏样本，以进行组织病理学检查，并测定抗氧化酶（谷胱甘肽过氧化物酶，超氧化物歧化酶）和丙二醛（MDA）水平。镉胁迫下鱼类组织中GPx和SOD的活性明显低于对照组（P <0.05）。镉暴露组中的MDA水平升高（P <0.05），而接受含有腐殖酸镉的鱼的肝脏中MDA水平恢复正常。腐殖酸也减少了镉诱导的组织病理学改变。这些结果表明，腐殖酸可能介导镉的毒性。

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