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首页> 外文期刊>Vascular and endovascular surgery >Comparison of Drug-Eluting Balloon and Standard Balloon Angioplasty for Infrapopliteal Arterial Diseases in Diabetic Patients
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Comparison of Drug-Eluting Balloon and Standard Balloon Angioplasty for Infrapopliteal Arterial Diseases in Diabetic Patients

机译:糖尿病患者pop下动脉疾病的药物洗脱球囊与标准球囊血管成形术的比较

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摘要

Objective: To consider the clinical outcomes and restenosis rates of drug-eluting balloons (DEBs) and percutaneous transluminal angioplasty (PTA) in diabetic patients with infrapopliteal (IP) arterial disease. Materials and Methods: This retrospective, single-center study included 51 patients (37 males; mean age: 63.43 +/- 9.81 years) with diabetes mellitus having IP arterial disease, from October 2012 to September 2014. Twenty-two patients were treated with PTA, and 29 patients were treated with DEBs. After intervention, the patients were evaluated in the first week and every 3 months, clinically and radiologically. Univariate and multivariate analyses were used to evaluate the clinical outcomes of diabetic patients with IP arterial disease who were treated with either DEBs or PTA. Results: There were no statistically significant differences between the groups in terms of age and gender, risk factors, characteristics of lesions, or the diameters or length of the balloons (P > .05). Primary patency was higher in the DEB group than in the PTA group (97.8% vs 81.1%, P = .020) in the first 3 months. However, there was no statistically significant difference at 1-year follow-up (68.2% vs 48.5%, P = .131). At the 12-month follow-up, there was no difference in clinical improvement between the groups (P = .193). Conclusion: The findings of this study reveal that DEB is a safe alternative treatment method for IP arterial disease in diabetic patients.
机译:目的:探讨糖尿病伴IP下(IP)动脉疾病患者的药物洗脱球囊(DEBs)和经皮腔内血管成形术(PTA)的临床结局和再狭窄率。材料和方法:该回顾性单中心研究纳入了2012年10月至2014年9月的51例患有IP动脉疾病的糖尿病患者(37例男性,平均年龄:63.43 +/- 9.81岁)。22例患者接受了PTA和29例患者接受DEB治疗。干预后,在第一周和每三个月对患者进行临床和放射学评估。单因素和多因素分析用于评估接受DEBs或PTA治疗的患有IP动脉疾病的糖尿病患者的临床结局。结果:两组之间在年龄和性别,危险因素,病变特征,或球囊直径或长度方面均无统计学差异(P> .05)。在头三个月中,DEB组的原发通畅率高于PTA组(97.8%对81.1%,P = .020)。但是,在1年的随访中,差异无统计学意义(68.2%对48.5%,P = .131)。在12个月的随访中,两组之间的临床改善无差异(P = .193)。结论:这项研究的结果表明,DEB是糖尿病患者IP动脉疾病的一种安全的替代治疗方法。

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