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首页> 外文期刊>Veterinary Dermatology >Sporotrichosis: a retrospective evaluation of 23 cases seen in northern California (1987-2007)
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Sporotrichosis: a retrospective evaluation of 23 cases seen in northern California (1987-2007)

机译：孢子菌病：回顾性评估23例在加利福尼亚北部（1987-2007）

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摘要

Sporotrichosis is an uncommon to rare cutaneous and subcutaneous mycosis of animals and humans caused by the dimorphic fungus Sporothrix schenckii. Twenty-three mammalian cases of sporotrichosis examined between 1987 and 2007 at the University of California, Davis - Veterinary Medical Teaching Hospital, were retrospectively evaluated with regard to the historical, clinical, diagnostic and treatment findings. Cats were the most common species affected (n = 14). In addition, sporotrichosis was diagnosed in four dogs, four horses and a donkey. Six of 23 cases were diagnosed with the localized cutaneous form of sporotrichosis (four cats, one dog, one horse), 10 with the cutaneous-lymphatic form (four cats, two dogs, three horses and a donkey), and seven with the disseminated form (six cats, one dog). Two of 23 cases did not have skin lesions at the time of diagnosis (one cat, one dog). The most common mode of diagnosis was demonstration of S. schenckii on histopathological evaluation of tissue. In contrast with most previously described sporotrichosis infections in cats, few to no fungal organisms were seen in histopathological samples (haematoxylin and eosin and special stains) in five of the 14 cats. Treatments received included itraconazole (12 cats, one dog), ketoconazole (three dogs), fluconazole (one cat, one donkey), sodium iodide (four horses, one cat) and potassium iodide (one cat, one horse, one donkey). The prognosis for successful treatment was good in all species. Fluconazole was successful in inducing resolution of the cutaneous lesions and controlling the infection in one cat with disseminated sporotrichosis.
机译：孢子菌病是由双形真菌Schenothrix schenckii引起的罕见的动物和人类皮下和皮下真菌病。 1987年至2007年在加利福尼亚大学戴维斯分校-兽医医学教学医院检查的23例孢子虫病哺乳动物病例，根据历史，临床，诊断和治疗结果进行了回顾性评估。猫是受影响最常见的物种（n = 14）。此外，在四只狗，四匹马和一头驴中被诊断出孢子虫病。 23例中有6例被诊断为局部皮肤形式的孢子虫病（四只猫，一只狗，一匹马），10例被诊断为皮肤淋巴样形式（四只猫，两只狗，三匹马和一头驴），七例被传播形式（六只猫，一只狗）。在诊断时23例中有2例没有皮肤病变（一只猫，一只狗）。最常见的诊断方法是在组织的组织病理学评估中证实申氏链球菌。与大多数先前描述的猫孢子体增生感染相反，在14只猫中有5只在组织病理学样本（苏木精和曙红及特殊染色剂）中未见到真菌生物。接受的治疗包括伊曲康唑（12只猫，一只狗），酮康唑（三只狗），氟康唑（一只猫，一只驴），碘化钠（四匹马，一只猫）和碘化钾（一只猫，一匹马，一只驴）。在所有物种中成功治疗的预后良好。氟康唑成功诱导了皮肤病灶的消退并控制了一只散发性孢子体病的猫的感染。

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