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Breed-associated phenotypes in canine atopic dermatitis.

机译:犬特应性皮炎中与繁殖相关的表型。

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Canine atopic dermatitis is a multifaceted disease, whose clinical presentation may be affected by numerous factors, including the genetic background of the animal, the environment, the offending allergens and flare factors. In particular, breed-associated differences have often been mentioned but never defined precisely. Using a large data set of atopic dogs, we document in this study the clinical presentation of nine often-affected breeds and demonstrate the existence of substantial differences between the clinical phenotype of each breed and the whole population. Some of the differences may be due to genetic differences while others are most likely to be associated with variations in environmental factors.Digital Object Identifier http://dx.doi.org/10.1111/j.1365-3164.2010.00925.x
机译:犬特应性皮炎是一种多方面的疾病,其临床表现可能受到多种因素的影响,包括动物的遗传背景,环境,有害的过敏原和耀斑因素。特别是,经常提到与品种相关的差异,但从未明确定义。使用大量的特应性狗,我们在这项研究中记录了9个经常受影响的品种的临床表现,并证明了每个品种的临床表型与整个种群之间存在实质性差异。一些差异可能是由于遗传差异引起的,而其他差异则最有可能与环境因素的变化有关。数字对象标识符http://dx.doi.org/10.1111/j.1365-3164.2010.00925.x

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