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首页> 外文期刊>Twin research and human genetics : >The Norwegian Institute of Public Health twin study of mental health: examining recruitment and attrition bias.
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The Norwegian Institute of Public Health twin study of mental health: examining recruitment and attrition bias.

机译：挪威公共卫生研究所对心理健康的双胞胎研究：检查招募和减员偏向。

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All Norwegian twin pairs born 1967-1974 and still living in Norway in 1992 were invited to a health questionnaire study (Q1). 2,570 pairs (65%) participated. These cohorts and the twin cohorts born 1967-1979 were invited to a new questionnaire study (Q2) in 1998. This time 3,334 pairs (53%) participated. Almost all pairs having participated in the 1998 study were invited to an interview study of mental health (MHS), taking place 1999-2004. 1,391 complete pairs (44%) participated. The questionnaire studies included extensive data on somatic health with fewer items on mental health and demography. Health-related and demographic information available from the Medical Birth Registry on all invited twins was applied to predict participation to the first study. A few registry variables indicating poor health predicted nonparticipation in Q1. Health information and demography from Q1 were tested as predictors of participation in the follow-up study (Q2). Monozygosity, female sex, being unmarried, having no children, and high education predicted participation, whereas few indicators of poor mental and somatic health and unhealthy lifestyle moderately predicted nonparticipation in Q2. No health indicators reported in Q2 predicted further participation. Standard genetic twin analyses of indicators of various mental disorders from Q2, validated by diagnostic data from the MHS, did not indicate differences in genetic/environmental covariance structures between participants and nonparticipants in MHS. In general the results show a moderate selection towards good mental and somatic health. Attrition from Q2 to the MHS does not appear to affect twin analyses of mental health related variables.
机译：邀请所有出生于1967-1974年，并于1992年仍生活在挪威的挪威双胞胎进行健康调查问卷研究（第一季度）。 2,570对（65％）参加了。这些队列和1967-1979年出生的双胞胎队列在1998年被邀请参加新的问卷调查（Q2）。这次有3,334对（53％）参加。几乎所有参加过1998年研究的人都被邀请参加了1999-2004年进行的心理健康访谈研究。 1,391对（44％）对参加了比赛。问卷调查研究包括关于身体健康的大量数据，而关于心理健康和人口统计学的项目较少。可从所有出生的双胞胎的医疗出生登记处获得的健康相关和人口统计学信息用于预测参与第一个研究的人数。一些表明健康状况不佳的注册表变量预测第一季度不参与。测试了来自第一季度的健康信息和人口统计学，作为参与后续研究（第二季度）的预测指标。单性，女性，未婚，没有孩子和受过高等教育可以预测参与，而很少有精神和身体健康状况差以及生活方式不健康的指标适度地预测第二季度不参与。第二季度未报告任何健康指标预测会进一步参与。通过MHS的诊断数据验证的第二季度各种精神障碍指标的标准遗传双胞胎分析未显示MHS参与者和非参与者之间遗传/环境协方差结构的差异。总体而言，结果表明对健康的身心健康选择得当。从第二季度到MHS的减员似乎不会影响对心理健康相关变量的双重分析。

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