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首页> 外文期刊>Veterinarni Medicina >Leukocyte counts and lymphocyte subpopulations in the peripheral blood of pygmy goats from herd infected with Mycobacterium avium subspecies paratuberculosis.
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Leukocyte counts and lymphocyte subpopulations in the peripheral blood of pygmy goats from herd infected with Mycobacterium avium subspecies paratuberculosis.

机译：感染鸟分枝杆菌亚种副结核菌群的矮山羊的外周血中白细胞计数和淋巴细胞亚群。

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摘要

Total and differential leukocyte counts and lymphocyte subpopulations in the peripheral blood of 11 pygmy goats in a zoo in the Czech Republic were studied. Lymphocyte subpopulations were enumerated by flow cytometry using monoclonal antibodies against surface antigens of bovine or ovine leukocytes, but not all of these cross-reacted, so only CD2, 5, 8, 11a/18, 18, 14 and B-cells were calculated. Goats were divided into 2 groups according to age: 3 were 4-6 months old and 8 were adult (3-6 years).Adult goats had significantly more neutrophils and fewer lymphocytes than younger goats; however adult goats had significantly more T-lymphocytes and fewer B-lymphocytes. Two goats (1 in each age group) were shedding M. avium subsp. paratuberculosis without clinical signs of the disease and had leukocyte counts and lymphocyte subsets comparable with results obtained from other goats in their group.
机译：在捷克共和国的一家动物园中，研究了11只侏儒山羊的外周血中总白细胞计数和差异白细胞计数以及淋巴细胞亚群。使用针对牛或绵羊白细胞表面抗原的单克隆抗体，通过流式细胞术计数淋巴细胞亚群，但并非所有这些交叉反应，因此仅计算了CD2、5、8、11a / 18、18、14和B细胞。山羊按年龄分为两组：3只在4-6个月大，8只在成年（3-6岁）。成年山羊的中性粒细胞明显增多，而淋巴细胞则少得多。但是成年山羊的T淋巴细胞明显多于B淋巴细胞。两只山羊（每个年龄组1只）正在脱落鸟分枝杆菌亚种。没有该疾病临床症状的副结核病，且白细胞计数和淋巴细胞亚群可与本组其他山羊的结果相媲美。

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