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首页> 外文期刊>Veterinary Pathology >Primary Intestinal and Vertebral Chordomas in Laboratory Zebrafish (Danio rerio)
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Primary Intestinal and Vertebral Chordomas in Laboratory Zebrafish (Danio rerio)

机译：实验室斑马鱼（Danio rerio）的原发性肠和椎脊索瘤

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摘要

Chordomas are uncommon neoplasms arising from notochord remnants, most commonly occurring in the axial skeleton. Extraskeletal soft tissue chordomas are rare primary tumors, and primary alimentary tract chordomas have not been reported. Herein we report 24 cases of spontaneous primary intestinal chordomas in zebrafish, as well as 9 spontaneous vertebral chordomas. Both intestinal and vertebral tumors showed invasive behavior, although more commonly in the latter. In all cases of primary intestinal chordomas, there was no axial or peripheral skeletal or other nonvisceral involvement. Although uncommon, intestinal chordomas represent a unique background lesion in aged zebrafish.
机译：脊索瘤是由脊索残余产生的罕见肿瘤，最常见于轴向骨骼。骨骼外软组织脊索瘤是罕见的原发性肿瘤，尚未见到原发性消化道脊索瘤。在这里，我们报告斑马鱼自发性原发性肠脊索瘤24例，以及9例自发性脊椎脊索瘤。肠道和椎骨肿瘤均表现出侵袭性，尽管在后者中更为常见。在所有原发性肠脊索瘤病例中，均无轴向或周围骨骼或其他非内脏受累。尽管不常见，但肠脊索瘤在老年斑马鱼中代表独特的背景病变。

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