首页> 外文期刊>Visual Neuroscience: An International Journal for Empirical and Theoretical Research >Gender-specific modulation of short-term neuroplasticity in the visual cortex induced by transcranial direct current stimulation.
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Gender-specific modulation of short-term neuroplasticity in the visual cortex induced by transcranial direct current stimulation.

机译:经颅直流电刺激引起的视觉皮层中短期神经可塑性的性别特异性调节。

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摘要

Transcranial direct current stimulation (tDCS) is a non-invasive method of modulating levels of cortical excitability. In this study, data gathered over a number of previously conducted experiments before and after tDCS, has been re-analyzed to investigate correlations between sex differences with respect to neuroplastic effects. Visual evoked potentials (VEPs), phosphene thresholds (PTs), and contrast sensitivity measurements (CSs) are used as indicators of the excitability of the primary visual cortex. The data revealed that cathodally induced excitability effects 10 min post stimulation with tDCS, showed no significant difference between genders. However, stimulation in the anodal direction revealed sex-specific effects: in women, anodal stimulation heightened cortical excitability significantly when compared to the age-matched male subject group. There was no significant difference between male and female subjects immediately after stimulation. These results indicate that sex differences exist within the visual cortex of humans, and may be subject to the influences of modulatory neurotransmitters or gonadal hormones which mirror short-term neuroplastic effects.
机译:经颅直流电刺激(tDCS)是调节皮层兴奋性水平的一种非侵入性方法。在这项研究中,已经重新分析了在tDCS之前和之后从许多先前进行的实验中收集的数据,以研究性别差异与神经塑性作用之间的相关性。视觉诱发电位(VEP),阈值(PTs)和对比敏感度测量值(CSs)用作主要视觉皮层兴奋性的指标。数据显示,tDCS刺激后10分钟,阴极诱导的兴奋性效应未显示性别差异。然而,在阳极方向上的刺激显示出特定于性别的作用:与年龄匹配的男性受试者组相比,在女性中,阳极刺激显着提高了皮层兴奋性。刺激后,男性和女性受试者之间没有显着差异。这些结果表明性别差异存在于人类的视觉皮层内,并可能受到反映短期神经增生作用的调节性神经递质或性腺激素的影响。

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