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首页> 外文期刊>The International journal of oral & maxillofacial implants >Maxillary Sinus Grafting with Autograft Versus Fresh-Frozen Allograft: A Split-Mouth Evaluation of Bone Volume Dynamics
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Maxillary Sinus Grafting with Autograft Versus Fresh-Frozen Allograft: A Split-Mouth Evaluation of Bone Volume Dynamics

机译：自体移植物与新鲜冷冻同种异体移植物的上颌窦移植：骨体积动力学的裂口评估

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Purpose: To compare volumetric changes after sinus augmentation of completely edentulous maxillae with either autogenous or allogeneic fresh-frozen bone particles. Materials and Methods: This split-mouth study in patients who required bilateral sinus grafting used autograft particles for one sinus and allograft particles for the contralateral sinus. The grafted sinuses were left to heal for 6 months prior to implant insertion. All patients underwent four computed tomography scans: prior to augmentation and 1 week, 6 months, and 12 months after grafting. Computer software was used to analyze bone graft volume in each scan. Results: Fifteen patients (8 men, 7 women) with a mean age of 54 +/- 5 years (range, 48 to 60 years) took part and underwent 30 sinus augmentation procedures. Mean autograft and allograft volumes were not statistically significantly different at each time point (1 week: 2.01 +/- 0.43 cm(3) vs 2.46 +/- 0.79 cm(3); 6 months: 1.53 +/- 0.49 cm(3) vs 1.75 +/- 0.64 cm(3); and 12 months: 1.38 +/- 0.43 cm(3) vs 1.59 +/- 0.56 cm(3), respectively). Mean volumetric reductions of 31.35% and 35.36% (23.9% and 29.9% in the 6 months prior to implant insertion, followed by an additional 9% and 9% in the following 6 months), relative to 1 week postgrafting, were noted for the autograft and allograft groups, respectively, after 12 months. Conclusion: On the basis of this split-mouth study of 15 patients, there was no statistically significant volumetric difference after 12 months between the use of autograft or allografts for sinus augmentation. Fresh-frozen bone allograft may serve as an alternative that avoids the morbidity associated with autograft harvesting.
机译：目的：比较自体或同种异体新鲜冷冻骨颗粒对完全无牙颌上颌窦增大后的容积变化。材料和方法：这项对需要双侧鼻窦移植的患者进行的分口研究使用了一个鼻窦的自体移植颗粒和对侧鼻窦的同种异体移植颗粒。在植入植入物之前，将嫁接的鼻窦愈合6个月。所有患者均接受了四次计算机断层扫描：增强前和移植后1周，6个月和12个月。在每次扫描中使用计算机软件来分析骨移植物的体积。结果：平均年龄为54 +/- 5岁（范围为48至60岁）的15例患者（男8例，女7例）参加了该手术并接受了30次鼻窦增高手术。自体移植和同种异体移植的平均体积在每个时间点均无统计学差异（1周：2.01 +/- 0.43 cm（3）vs 2.46 +/- 0.79 cm（3）; 6个月：1.53 +/- 0.49 cm（3） vs. 1.75 +/- 0.64 cm（3）;和12个月：1.38 +/- 0.43 cm（3）和1.59 +/- 0.56 cm（3）。相对于移植后1周，平均体积减少了31.35％和35.36％（在植入植入物之前的6个月中分别降低了23.9％和29.9％，在接下来的6个月中分别降低了9％和9％）。自体移植和同种异体移植组分别在12个月后。结论：根据这项对15例患者的分口研究，使用自体移植或同种异体移植进行鼻窦增厚之间12个月后，在体积上无统计学差异。新鲜冷冻的同种异体骨可以作为避免自体移植相关疾病的替代方法。

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