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首页> 外文期刊>The International journal of pharmacy practice >Patients using antifungals following laryngectomy: A qualitative study of community pharmacists in the North of England
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Patients using antifungals following laryngectomy: A qualitative study of community pharmacists in the North of England

机译：喉切除术后使用抗真菌药的患者：英格兰北部社区药剂师的定性研究

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Objective To explore community pharmacists' understanding and opinions in relation to the prevention of fungal colonisation of voice prostheses amongst laryngectomy patients. Method Semi-structured interviews were conducted on a purposive sample of 12 community pharmacists from the North of England. Interviews were undertaken until data saturation was reached and responses were transcribed verbatim and analysed using a thematic approach. Key findings Six themes emerged from the data analysis. These were: terminology confusion about laryngectomy, stoma and voice prostheses; smoking as a risk factor for the development of laryngeal cancer; using nystatin to prevent biofilm formation; counselling information related to nystatin; prescription intervention and additional education in relation to laryngectomy. The theme of counselling information related to nystatin use and additional education was a key finding: our data show that when dispensing nystatin to patients with a voice prosthesis, community pharmacists would either give no advice related to medication use or would give incorrect advice that may lead to premature prosthesis failure amongst this patient group. Conclusion This study highlights that community pharmacists lack understanding in relation to laryngectomy and are unaware of the off-label doses and administration methods of the drugs (specifically nystatin) used to prevent fungal colonisation on voice prostheses. Additional information sources in the form of an educational leaflet, possibly obtained through the local department of speech and language therapy, would be perceived as a valuable resource to support community pharmacists who are required to manage these patients in the community.
机译：目的探讨社区药剂师在预防喉切除术患者语音假体真菌定植方面的理解和看法。方法对来自英格兰北部的12位社区药剂师的目标样本进行了半结构化访谈。进行访谈，直到达到数据饱和，并逐字记录答复并使用主题方法进行分析。主要发现数据分析提出了六个主题。它们是：关于喉切除术，造口和语音假体的术语混淆;吸烟是喉癌发展的危险因素;使用制霉菌素防止生物膜形成;与制霉菌素有关的咨询信息;与喉切除术有关的处方干预和额外教育。咨询有关制霉菌素使用和进一步教育的信息的主题是一个关键发现：我们的数据表明，将制霉菌素分配给有语音假肢的患者时，社区药师可能不会提供任何与药物使用有关的建议，或者会提供可能导致不正确使用的建议导致该患者组中的假体过早失效。结论该研究强调，社区药剂师对喉切除术缺乏了解，并且不了解用于预防语音假肢真菌定植的药物（特别是制霉菌素）的超标剂量和给药方法。可以通过当地言语和语言治疗部门获得的教育传单形式的其他信息源，将被视为支持社区药师的宝贵资源，这些药师需要在社区中管理这些患者。

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