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Implementation of a method for glucose measurements in community pharmacies.

机译:社区药房中葡萄糖测量方法的实现。

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OBJECTIVES: We aimed to implement a method for glucose measurements that could be used as a comparison method for asessing patients' self-monitoring of blood glucose. Further, we investigated whether pharmacies could achieve an analytical quality comparable to glucose measurements performed in general practice. METHODS: Sixteen Norwegian pharmacy employees were trained in glucose measurement, quality control and blood sampling. The comparison method, HemoCue Glucose 201+, was validated in four steps: (1) estimation of the variation between the HemoCue instruments to be used at the 16 pharmacies, (2) comparison between HemoCue results and a laboratory glucose method, (3) monitoring quality by internal quality controls and (4) an external quality-assessment scheme. The pharmacies' results of the external quality assessment were compared to those of 359 general practices. KEY FINDINGS: The coefficient of variation for HemoCue instruments was 6.1% at the low level and 1.7% at the normal and high levels. Bias was negligible at the normal level. The coefficients of variation for internal quality controls were 4.5, 1.5 and 1.2% for the low, normal and high levels, respectively. All pharmacies achieved good precision and acceptable or good trueness in the external quality assessment. The pharmacies exhibited significantly lower variation between sites (2.2 and 1.2%) than general practices (3.8 and 2.9%) on both external quality-assessment samples. CONCLUSIONS: Given correct training and the establishment of a system of quality assurance, pharmacies are capable of obtaining glucose measurements that can be used as comparison measurements for controlling patients' meters. The pharmacies had external quality-assessment results comparable to general practice.
机译:目的:我们旨在实施一种血糖测量方法,该方法可以用作评估患者自我血糖监测的比较方法。此外,我们调查了药房是否可以达到与一般实践中进行的葡萄糖测量相当的分析质量。方法:十六名挪威药房员工接受了葡萄糖测量,质量控制和血液采样方面的培训。比较方法HemoCue葡萄糖201+的验证通过四个步骤进行:(1)估计16家药店使用的HemoCue仪器之间的差异,(2)HemoCue结果与实验室葡萄糖方法之间的比较,(3)通过内部质量控制和(4)外部质量评估计划来监控质量。将药房的外部质量评估结果与359种常规做法进行了比较。主要发现:HemoCue仪器的变异系数在低水平为6.1%,在正常水平和高水平为1.7%。在正常水平上,偏差可以忽略不计。对于低,正常和高水平,内部质量控制的变异系数分别为4.5%,1.5%和1.2%。所有药房在外部质量评估中均达到了良好的精度和可接受性或良好性。在两个外部质量评估样本上,药房之间的差异(2.2和1.2%)明显低于一般做法(3.8和2.9%)。结论:经过正确的培训和质量保证体系的建立,药房有能力获得葡萄糖测量值,可以用作控制患者仪表的比较测量值。这些药房的外部质量评估结果可与一般实践相媲美。

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